Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50004402
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50235738(Hippuristanol)
Affinity DataIC50:  400nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482563(CHEMBL449854 | Hippurin-1)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482566(CHEMBL1222376)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482552(CHEMBL507260)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482553(CHEMBL1222377)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482550(CHEMBL1222374 | Hippuristanol 11-One)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482560(CHEMBL1222308 | Hippuristanol 3-Acetate)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482559(CHEMBL457151)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482565(CHEMBL1221511)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482551(CHEMBL1222375 | Hippuristanol 3,11-Dione)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482557(CHEMBL506697)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482562(CHEMBL1222309 | Hippuristanol 3,11-Diacetate)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482558(Hippuristanohemiacetal)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482561(CHEMBL1221461 | Epihippuristanol 3,11-Diacetate)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482556(Epihippurin 1)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482554(CHEMBL1221460 | Epihippuristanol 3-Acetate)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482564(CHEMBL1221464 | Epihippuristanol 3,11-Dione)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482567(22-Epi-Hippuristanol | Epihippuristanol)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50482555(CHEMBL1221463 | Epihippuristanol 11-One)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed