Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50004402
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235738BDBM50235738(Hippuristanol)
Affinity DataIC50: 400nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482563BDBM50482563(Hippurin-1 | CHEMBL449854)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482566BDBM50482566(CHEMBL1222376)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482552BDBM50482552(CHEMBL507260)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482553BDBM50482553(CHEMBL1222377)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482550BDBM50482550(Hippuristanol 11-One | CHEMBL1222374)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482560BDBM50482560(Hippuristanol 3-Acetate | CHEMBL1222308)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482559BDBM50482559(CHEMBL457151)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482565BDBM50482565(CHEMBL1221511)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482557BDBM50482557(CHEMBL506697)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482551BDBM50482551(Hippuristanol 3,11-Dione | CHEMBL1222375)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482562BDBM50482562(Hippuristanol 3,11-Diacetate | CHEMBL1222309)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482558BDBM50482558(Hippuristanohemiacetal)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482554BDBM50482554(Epihippuristanol 3-Acetate | CHEMBL1221460)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482555BDBM50482555(Epihippuristanol 11-One | CHEMBL1221463)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482556BDBM50482556(Epihippurin 1)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482564BDBM50482564(Epihippuristanol 3,11-Dione | CHEMBL1221464)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482567BDBM50482567(22-Epi-Hippuristanol | Epihippuristanol)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482561BDBM50482561(Epihippuristanol 3,11-Diacetate | CHEMBL1221461)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed