Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50017599
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184391BDBM50184391((R,Z)-2-(2-(hydroxymethyl)-4-(3-isobutyl-5-methylh...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107112BDBM50107112(DAG-lactone (HK-434) | (Z) 2,2-Dimethyl-propionic ...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184395BDBM50184395(5-hexanoyloxymethyl-5-hydroxymethyl-3-[(Z)-3-isobu...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107120BDBM50107120(2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-[3-i...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107118BDBM50107118(3-Isopropyl-4-methyl-pentanoic acid 2-hydroxymethy...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184385BDBM50184385(5-hydroxymethyl-3-[(Z)-3-isobutyl-5-methylhexylide...)
Affinity DataKi:  5nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184380BDBM50184380(5-hydroxymethyl-3-[(E)-3-isobutyl-5-methylhexylide...)
Affinity DataKi:  6nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184382BDBM50184382(5-hexanoyloxymethyl-5-hydroxymethyl-3-[(E)-3-isobu...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184390BDBM50184390(5-benzoyloxymethyl-5-hydroxymethyl-3-[(Z)-3-isobut...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184388BDBM50184388(5-hydroxymethyl-3-[(Z)-3-isobutyl-5-methylhexylide...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50107116BDBM50107116(3-Isopropyl-4-methyl-pentanoic acid 2-hydroxymethy...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184383BDBM50184383(5-benzoyloxymethyl-5-hydroxymethyl-3-[(E)-3-isobut...)
Affinity DataKi:  16nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184392BDBM50184392(5-[(E)-3-(tert-butoxy)-3-oxo-1-propenyl]-5-hydroxy...)
Affinity DataKi:  18nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184384BDBM50184384(6-hydroxymethyl-3-[(Z)-3-isobutyl-5-methylhexylide...)
Affinity DataKi:  28nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184394BDBM50184394(6-hydroxymethyl-3-[(E)-3-isobutyl-5-methylhexylide...)
Affinity DataKi:  48nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184386BDBM50184386(6-hydroxymethyl-3-[(E)-3-isobutyl-5-methylhexylide...)
Affinity DataKi:  129nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184381BDBM50184381(6-hydroxymethyl-3-[(E)-3-isobutyl-5-methylhexylide...)
Affinity DataKi:  147nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184389BDBM50184389(5-[(E)-3-(tert-butoxy)-3-oxo-1-propenyl]-5-hydroxy...)
Affinity DataKi:  173nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184387BDBM50184387(5-(hydroxymethyl)-5-(pivaloyloxymethyl)-3,3-bis(3-...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184379BDBM50184379(5-(hydroxymethyl)-5-(pivaloyloxymethyl)-3,3-bis(3-...)
Affinity DataKi:  1.83E+4nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Research Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184393BDBM50184393(5-[(Z)-3-(tert-butoxy)-3-oxo-1-propenyl]-5-hydroxy...)
Affinity DataKi:  2.17E+4nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed