Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50041458
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataEC50:  1nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  8nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataEC50:  52nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataEC50:  57nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411077(CHEMBL212430)
Affinity DataEC50:  90nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411075(CHEMBL208593)
Affinity DataEC50:  100nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataEC50:  200nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataEC50:  300nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411080(CHEMBL379575)
Affinity DataEC50:  310nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411073(CHEMBL211343)
Affinity DataEC50:  670nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411081(CHEMBL208918)
Affinity DataEC50:  1.80E+3nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411079(CHEMBL379190)
Affinity DataEC50:  2.49E+3nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411078(CHEMBL211326)
Affinity DataEC50:  2.72E+3nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411076(CHEMBL210820)
Affinity DataEC50:  3.36E+3nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataEC50:  3.90E+3nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411081(CHEMBL208918)
Affinity DataEC50:  4.91E+3nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411079(CHEMBL379190)
Affinity DataEC50:  5.10E+3nMAssay Description:Antiviral activity against HIV1 Y181C mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411078(CHEMBL211326)
Affinity DataEC50:  6.52E+3nMAssay Description:Antiviral activity against HIV1 Y181C mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataEC50: >7.50E+3nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataEC50: >7.50E+3nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411075(CHEMBL208593)
Affinity DataEC50:  8.01E+3nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411078(CHEMBL211326)
Affinity DataEC50:  8.68E+3nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411081(CHEMBL208918)
Affinity DataEC50:  1.21E+4nMAssay Description:Antiviral activity against HIV1 Y181C mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411077(CHEMBL212430)
Affinity DataEC50:  1.67E+4nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411080(CHEMBL379575)
Affinity DataEC50:  2.58E+4nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411074(CHEMBL211344)
Affinity DataEC50:  2.65E+4nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411079(CHEMBL379190)
Affinity DataEC50: >2.76E+4nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411079(CHEMBL379190)
Affinity DataEC50: >2.76E+4nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411079(CHEMBL379190)
Affinity DataEC50: >2.76E+4nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411077(CHEMBL212430)
Affinity DataEC50:  4.25E+4nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411076(CHEMBL210820)
Affinity DataEC50:  4.47E+4nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411073(CHEMBL211343)
Affinity DataEC50: >5.75E+4nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411073(CHEMBL211343)
Affinity DataEC50: >5.75E+4nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411073(CHEMBL211343)
Affinity DataEC50: >5.75E+4nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411076(CHEMBL210820)
Affinity DataEC50: >6.05E+4nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411076(CHEMBL210820)
Affinity DataEC50: >6.05E+4nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411078(CHEMBL211326)
Affinity DataEC50: >6.13E+4nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411074(CHEMBL211344)
Affinity DataEC50: >6.14E+4nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411074(CHEMBL211344)
Affinity DataEC50: >6.14E+4nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411074(CHEMBL211344)
Affinity DataEC50: >6.14E+4nMAssay Description:Antiviral activity against HIV1 Y181C mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411074(CHEMBL211344)
Affinity DataEC50: >6.14E+4nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411078(CHEMBL211326)
Affinity DataEC50: >6.17E+4nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411080(CHEMBL379575)
Affinity DataEC50: >6.58E+4nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411080(CHEMBL379575)
Affinity DataEC50: >6.58E+4nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411075(CHEMBL208593)
Affinity DataEC50: >6.61E+4nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411075(CHEMBL208593)
Affinity DataEC50: >6.61E+4nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50411081(CHEMBL208918)
Affinity DataEC50: >6.63E+4nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
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