Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 1216
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10173(pyridin-4-ylmethyl N-[(1S)-1-{[(5R)-5-[(4-aminoben...)
Affinity DataKi:  0.0200nM IC50: 0.390nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10171(pyridin-2-ylmethyl N-[(1S)-1-{[(5R)-5-[(4-aminoben...)
Affinity DataKi:  0.400nM IC50: 0.120nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10170((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.340nM IC50: 0.240nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10177((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.330nM IC50: 0.330nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10172(pyridin-3-ylmethyl N-[(1S)-1-{[(5R)-5-[(4-aminoben...)
Affinity DataKi:  0.360nM IC50: 0.480nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10169((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.400nM IC50: 0.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10157(tert-butyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-...)
Affinity DataKi:  0.5nM IC50: 0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10175((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.400nM IC50: 0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10165((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.400nM IC50: 0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10166((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.5nM IC50: 0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10168((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.5nM IC50: 0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10155((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.450nM IC50: 0.430nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10161((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.470nM IC50: 0.430nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10158((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.580nM IC50: 0.440nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10162((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.440nM IC50: 0.460nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10179((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.450nM IC50: 0.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10176((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.470nM IC50: 0.530nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10178((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.480nM IC50: 0.560nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10153((2S)-2-amino-N-[(5R)-5-[(4-aminobenzene)(2-methylp...)
Affinity DataKi:  0.560nM IC50: 0.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10149(lysine sulfonamide analogue 13SS | methyl N-[(1S)-...)
Affinity DataIC50: 0.5nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10159((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.550nM IC50: 0.510nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10160((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.600nM IC50: 0.520nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10148(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 0.521nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10163((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.550nM IC50: 0.680nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10174((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.580nM IC50: 0.630nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10164((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.660nM IC50: 0.650nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10167((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.700nM IC50: 0.900nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10146(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 1.20nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10147(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 1.20nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10154((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataIC50: 1.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10156((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataIC50: 3.80nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10145(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 6.5nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10141(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 12nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10149(lysine sulfonamide analogue 13SS | methyl N-[(1S)-...)
Affinity DataIC50: 13nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10150(lysine sulfonamide analogue 13RR | methyl N-[(1R)-...)
Affinity DataIC50: 25nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10143(methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-meth...)
Affinity DataIC50: 40nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10144(lysine sulfonamide analogue 8)
Affinity DataIC50: 130nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10142(methyl N-[(S)-{[(5R)-5-[(4-aminobenzene)(2-methylp...)
Affinity DataIC50: 300nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10150(lysine sulfonamide analogue 13RR | methyl N-[(1R)-...)
Affinity DataIC50: 300nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed