Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50017760
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  8nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186103((R)-1-((3-(3-chlorobenzyl)-3-(2,2,2-trichloroaceta...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(CHEMBL378317 | N-((3-(N-(3-nitrobenzyl)-2,2,2-tric...)
Affinity DataIC50:  14nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186113((R)-1-((3-benzyl-3-(2,2,2-trichloroacetamido)cyclo...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186116(CHEMBL209024 | rac-1-((3-(N-benzylpivalamido)cyclo...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186105(CHEMBL382613 | rac-N-((3-(N-(3-chlorobenzyl)-2,2,2...)
Affinity DataIC50:  21nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(CHEMBL379665 | rac-N-((3-(N-benzylpivalamido)cyclo...)
Affinity DataIC50:  24nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186109(CHEMBL209333 | rac-N-((3-(N-benzyl-2,2,2-trichloro...)
Affinity DataIC50:  27nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(CHEMBL379665 | rac-N-((3-(N-benzylpivalamido)cyclo...)
Affinity DataIC50:  29nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186106(CHEMBL210906 | rac-1-((3-(N-(3-nitrobenzyl)-2,2,2-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(CHEMBL382612 | rac-N-((3-(N-(3-chlorobenzyl)-2,2,2...)
Affinity DataIC50:  36nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(CHEMBL378317 | N-((3-(N-(3-nitrobenzyl)-2,2,2-tric...)
Affinity DataIC50:  52nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(CHEMBL382612 | rac-N-((3-(N-(3-chlorobenzyl)-2,2,2...)
Affinity DataIC50:  58nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186109(CHEMBL209333 | rac-N-((3-(N-benzyl-2,2,2-trichloro...)
Affinity DataIC50:  58nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186105(CHEMBL382613 | rac-N-((3-(N-(3-chlorobenzyl)-2,2,2...)
Affinity DataIC50:  63nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(CHEMBL438962 | N-(((1R,3S)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  72nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(CHEMBL378317 | N-((3-(N-(3-nitrobenzyl)-2,2,2-tric...)
Affinity DataIC50:  72nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186105(CHEMBL382613 | rac-N-((3-(N-(3-chlorobenzyl)-2,2,2...)
Affinity DataIC50:  228nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(CHEMBL382612 | rac-N-((3-(N-(3-chlorobenzyl)-2,2,2...)
Affinity DataIC50:  267nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  338nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(CHEMBL438962 | N-(((1R,3S)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  638nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186101(CHEMBL380678 | rac-1-((-3-(N-(3-chlorobenzyl)-3-me...)
Affinity DataIC50:  650nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186114(CHEMBL210923 | rac-1-((3-(N-benzylfuran-2-carboxam...)
Affinity DataIC50:  656nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186117(CHEMBL210447 | rac-1-((3-(N-benzyl-3-phenylpropana...)
Affinity DataIC50:  730nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186107(CHEMBL169509 | rac-1-((3-(N-benzylpivalamido)cyclo...)
Affinity DataIC50:  772nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186115(CHEMBL212044 | rac-1-((3-(N-benzyl-2,2,2-trichloro...)
Affinity DataIC50:  957nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(CHEMBL379665 | rac-N-((3-(N-benzylpivalamido)cyclo...)
Affinity DataIC50:  990nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186104(CHEMBL210899 | rac-1-((3-(N-benzyl-3-nitrobenzamid...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(CHEMBL438962 | N-(((1R,3S)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  2.48E+3nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed