Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50018050
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190487BDBM50190487(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 7nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190466BDBM50190466(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190462BDBM50190462(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 8nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190494BDBM50190494(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 9nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190486BDBM50190486(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190481BDBM50190481(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190459BDBM50190459(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190484BDBM50190484(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190468BDBM50190468(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190475BDBM50190475(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190489BDBM50190489((4-{4-[N-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190465BDBM50190465(1-(4-(4-aminophenyl)butyl)-3-(3,5-diamino-2-chloro...)
Affinity DataIC50: 21nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190458BDBM50190458(sulfuric acid mono-(4-{4-[N-(3,5-diamino-6-chlorop...)
Affinity DataIC50: 21nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190488BDBM50190488(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50: 22nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190480BDBM50190480(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[3-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190490BDBM50190490(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 26nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190493BDBM50190493(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 28nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190456BDBM50190456(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(4-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190471BDBM50190471(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190455BDBM50190455(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190478BDBM50190478(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[3-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190460BDBM50190460(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[2-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190457BDBM50190457(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190483BDBM50190483((4-{4-[N-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50: 48nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190479BDBM50190479(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190477BDBM50190477(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50: 51nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190461BDBM50190461(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(6-...)
Affinity DataIC50: 58nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190463BDBM50190463(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[2-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190464BDBM50190464(1-(3,5-diamino-2-chloropyrazine-6-carbonyl)-3-(5-(...)
Affinity DataIC50: 64nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190485BDBM50190485(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-phe...)
Affinity DataIC50: 66nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81819BDBM81819(NSC_108107 | CHEMBL212579 | CAS_1937-37-7 | Benzam...)
Affinity DataIC50: 66nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190470BDBM50190470(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(5-...)
Affinity DataIC50: 68nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190474BDBM50190474(6-(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbon...)
Affinity DataIC50: 73nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190495BDBM50190495(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[5-...)
Affinity DataIC50: 77nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190491BDBM50190491(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-hex...)
Affinity DataIC50: 87nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190472BDBM50190472(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[3-...)
Affinity DataIC50: 88nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190473BDBM50190473(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(2-...)
Affinity DataIC50: 107nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190492BDBM50190492(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-oct...)
Affinity DataIC50: 108nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190482BDBM50190482(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[3-...)
Affinity DataIC50: 124nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 115076BDBM115076(cid_9604979 | 3,5-diamino-N-[amino(anilino)methyli...)
Affinity DataIC50: 401nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190469BDBM50190469(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(8-...)
Affinity DataIC50: 477nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16173BDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataIC50: 776nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed