Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 1669
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13165(2,5-dihydroxy-3-(2-{3-[2-(3-methylphenyl)ethyl]phe...)
Affinity DataKi:  180nM ΔG°:  -38.1kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13164(2,5-dihydroxy-3-{2-[3-(2-phenylethyl)phenyl]ethyl}...)
Affinity DataKi:  380nM ΔG°:  -36.3kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13158(2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dio...)
Affinity DataKi:  400nM ΔG°:  -36.2kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13163(3-[2-(3-butylphenyl)ethyl]-2,5-dihydroxycyclohexa-...)
Affinity DataKi:  480nM ΔG°:  -35.7kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13162(2,5-dihydroxy-3-(2-phenylethyl)cyclohexa-2,5-diene...)
Affinity DataKi:  710nM ΔG°:  -34.7kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13160(2,5-dihydroxy-3-octylcyclohexa-2,5-diene-1,4-dione...)
Affinity DataKi:  1.25E+3nM ΔG°:  -33.4kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13161(2,5-dihydroxy-3-(4-phenylbutyl)cyclohexa-2,5-diene...)
Affinity DataKi:  1.30E+3nM ΔG°:  -33.3kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13159(3-ethyl-2,5-dihydroxycyclohexa-2,5-diene-1,4-dione...)
Affinity DataKi:  1.04E+4nM ΔG°:  -28.2kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed