Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50018515
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM15797((1S,2R)-N-[1-(3,5-Difluorobenzyl)-2-hydroxy-3-(3-i...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196587(CHEMBL253800 | benzyl 1-((2S,3R)-4-(3-methoxybenzy...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196587(CHEMBL253800 | benzyl 1-((2S,3R)-4-(3-methoxybenzy...)
Affinity DataIC50:  112nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(CHEMBL253165 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human BACE in HEK293 cells by Swedish amyloid inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196582(CHEMBL254625 | N1-((2S,3R)-4-(3-iodobenzylamino)-3...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(CHEMBL401141 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  314nMAssay Description:Inhibition of human BACE in HEK293 cells by Swedish amyloid inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(CHEMBL253165 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  484nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196578(3-[({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZY...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(CHEMBL401141 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  596nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196576(CHEMBL252961 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196580(CHEMBL401338 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196592(CHEMBL398925 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  3.67E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196584(CHEMBL252960 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  3.79E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196591(CHEMBL254626 | N-((2S,3R)-4-(3-iodobenzylamino)-1-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196575(CHEMBL252547 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  4.13E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(CHEMBL253165 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  4.88E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196576(CHEMBL252961 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196580(CHEMBL401338 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  5.02E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196589(CHEMBL437961 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  5.21E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196583(CHEMBL252755 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  5.61E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196589(CHEMBL437961 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  6.04E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196577(CHEMBL252756 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  6.46E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196592(CHEMBL398925 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  6.95E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196579(CHEMBL252549 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  7.59E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196581(CHEMBL252962 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  7.95E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(CHEMBL401141 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  9.67E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196583(CHEMBL252755 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196588(CHEMBL399749 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196581(CHEMBL252962 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196577(CHEMBL252756 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196575(CHEMBL252547 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196590(CHEMBL252548 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196584(CHEMBL252960 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196585(CHEMBL252754 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196585(CHEMBL252754 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196590(CHEMBL252548 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196579(CHEMBL252549 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196588(CHEMBL399749 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed