Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50038005
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197608(8-(2-bromo-acetyl)-1,2,3,11-tetrahydro-5,11-diaza-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197588(8-{2-[((3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymet...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197610(8-acetyl-1,2,3,11-tetrahydro-5,11-diaza-benzo[a]tr...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197601(CHEMBL391403 | N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197585(10-(aminomethyl)-4,5,6,7-tetrahydro-1Hcyclopenta[a...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197598(CHEMBL397773 | N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahy...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197584(1-[4-(4,6-dioxo-2,3,4,5,6,11-hexahydro-1H-5,11-dia...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197607(CHEMBL246396 | N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahy...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197606(CHEMBL391402 | [4-(4,6-dioxo-2,3,4,5,6,11-hexahydr...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197583(8-[2-(2-methyl-propane-2-sulfonylmethyl)-thiazol-4...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197605(2-amino-5-[4-(4,6-dioxo-2,3,4,5,6,11-hexahydro-1H-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197600(8-(2-amino-thiazol-4-yl)-1,2,3,11-tetrahydro-5,11-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197587(CHEMBL397399 | [4-(4,6-dioxo-2,3,4,5,6,11-hexahydr...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197597(CHEMBL246128 | N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahy...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177482(1,2,3,11-Tetrahydro-5,11-diaza-benzo[a]trindene-4,...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197599(8-(2-methanesulfonylmethyl-thiazol-4-yl)-1,2,3,11-...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197604(8-(2-methyl-thiazol-4-yl)-1,2,3,11-tetrahydro-5,11...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197592(CHEMBL397532 | N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahy...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197609(8-(2-aminomethyl-thiazol-4-yl)-1,2,3,11-tetrahydro...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197593(2-tert-butoxycarbonylamino-5-[4-(4,6-dioxo-2,3,4,5...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197595(CHEMBL246548 | cyclopropanecarboxylic acid [4-(4,6...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197591(8-(2-amino-5-methyl-thiazol-4-yl)-1,2,3,11-tetrahy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197603(CHEMBL246750 | cyclopentanecarboxylic acid [4-(4,6...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197586(CHEMBL245735 | N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahy...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197596(8-(2-methylamino-thiazol-4-yl)-1,2,3,11-tetrahydro...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197611(CHEMBL246592 | N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahy...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197590(CHEMBL395610 | pentanoic acid [4-(4,6-dioxo-2,3,4,...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197589(CHEMBL246547 | N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahy...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197602(2,2-dimethyl-propionic acid 4-(4,6-dioxo-2,3,4,5,6...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197594(8-(2-isoxazol-5-yl-thiazol-4-yl)-1,2,3,11-tetrahyd...)
Affinity DataIC50:  66nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197582(8-(5-bromo-2-methyl-thiazol-4-yl)-1,2,3,11-tetrahy...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed