Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 1733
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13760BDBM13760((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13768BDBM13768(N-[(1R,2S,5R,7S)-5-[(carbamoylmethyl)carbamoyl]ada...)
Affinity DataIC50: 4nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13756BDBM13756((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 4nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13761BDBM13761((1R,3R,4S,7S)-4-[2-(4-methoxyphenoxy)-2-methylprop...)
Affinity DataIC50: 4nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13756BDBM13756((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 5nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13760BDBM13760((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 6nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13770BDBM13770(2-(4-chlorophenoxy)-N-[(1R,2S,5R,7S)-5-(hydroxymet...)
Affinity DataIC50: 6nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13761BDBM13761((1R,3R,4S,7S)-4-[2-(4-methoxyphenoxy)-2-methylprop...)
Affinity DataIC50: 6nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13757BDBM13757((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 8nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13769BDBM13769(2-(4-chlorophenoxy)-2-methyl-N-[(1R,2S,5R,7S)-5-{[...)
Affinity DataIC50: 8nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13757BDBM13757((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 8nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13770BDBM13770(2-(4-chlorophenoxy)-N-[(1R,2S,5R,7S)-5-(hydroxymet...)
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13772BDBM13772(2-(2-chloro-4-fluorophenoxy)-2-methyl-N-[(1R,2S,5R...)
Affinity DataIC50: 10nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13772BDBM13772(2-(2-chloro-4-fluorophenoxy)-2-methyl-N-[(1R,2S,5R...)
Affinity DataIC50: 11nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13766BDBM13766((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 11nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13768BDBM13768(N-[(1R,2S,5R,7S)-5-[(carbamoylmethyl)carbamoyl]ada...)
Affinity DataIC50: 12nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13762BDBM13762(4-({[(1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methyl...)
Affinity DataIC50: 12nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13769BDBM13769(2-(4-chlorophenoxy)-2-methyl-N-[(1R,2S,5R,7S)-5-{[...)
Affinity DataIC50: 13nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13767BDBM13767((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 14nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13758BDBM13758((1R,3R,4S,7S)-4-[2-(3-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 15nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13762BDBM13762(4-({[(1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methyl...)
Affinity DataIC50: 15nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13764BDBM13764((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 16nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13764BDBM13764((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 18nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13759BDBM13759((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 22nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13765BDBM13765((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 24nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13763BDBM13763((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 25nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13767BDBM13767((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 25nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13763BDBM13763((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 25nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13766BDBM13766((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 27nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13773BDBM13773((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 28nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13755BDBM13755((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 39nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13758BDBM13758((1R,3R,4S,7S)-4-[2-(3-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 51nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13765BDBM13765((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 51nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13759BDBM13759((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 70nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13773BDBM13773((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 96nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13771BDBM13771(2-{[(1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylp...)
Affinity DataIC50: 110nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13755BDBM13755((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 119nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13757BDBM13757((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 140nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13771BDBM13771(2-{[(1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylp...)
Affinity DataIC50: 210nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13774BDBM13774((1R,3R,4S,7S)-N-(benzenesulfonyl)-4-[2-(2-chloroph...)
Affinity DataIC50: 500nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13758BDBM13758((1R,3R,4S,7S)-4-[2-(3-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 540nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13772BDBM13772(2-(2-chloro-4-fluorophenoxy)-2-methyl-N-[(1R,2S,5R...)
Affinity DataIC50: 550nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13773BDBM13773((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 580nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13774BDBM13774((1R,3R,4S,7S)-N-(benzenesulfonyl)-4-[2-(2-chloroph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13772BDBM13772(2-(2-chloro-4-fluorophenoxy)-2-methyl-N-[(1R,2S,5R...)
Affinity DataIC50: 1.20E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13773BDBM13773((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 1.20E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13755BDBM13755((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)
Affinity DataIC50: 1.50E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13759BDBM13759((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 1.70E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13757BDBM13757((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 1.80E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 13758BDBM13758((1R,3R,4S,7S)-4-[2-(3-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 3.50E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
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