Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50042258
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422978BDBM50422978(CHEMBL228586)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422961BDBM50422961(CHEMBL387969)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422971BDBM50422971(CHEMBL387878)
Affinity DataIC50: 0.630nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422986BDBM50422986(CHEMBL228593)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422973BDBM50422973(CHEMBL395248)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422974BDBM50422974(CHEMBL230765)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422977BDBM50422977(CHEMBL228963)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422983BDBM50422983(CHEMBL395488)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422963BDBM50422963(CHEMBL228638)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422981BDBM50422981(CHEMBL230766)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422967BDBM50422967(CHEMBL426913)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422972BDBM50422972(CHEMBL397655)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422964BDBM50422964(CHEMBL414978)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422975BDBM50422975(CHEMBL230875)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422976BDBM50422976(CHEMBL388294)
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422968BDBM50422968(CHEMBL228592)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422962BDBM50422962(CHEMBL228644)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422985BDBM50422985(CHEMBL374824)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422960BDBM50422960(GW855454X | CHEMBL231184)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422979BDBM50422979(CHEMBL228746)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422984BDBM50422984(CHEMBL228695)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187023BDBM50187023(3-(2-(2-(4-fluorobenzyloxy)-5-bromophenyl)-5-methy...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187023BDBM50187023(3-(2-(2-(4-fluorobenzyloxy)-5-bromophenyl)-5-methy...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422969BDBM50422969(CHEMBL388478)
Affinity DataIC50: 7.90nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422959BDBM50422959(CHEMBL390081)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422982BDBM50422982(CHEMBL230874)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422970BDBM50422970(CHEMBL388510)
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422965BDBM50422965(CHEMBL230873)
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422966BDBM50422966(CHEMBL397226)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422960BDBM50422960(GW855454X | CHEMBL231184)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant TP receptor expressed in CHO cells by calcium mobilisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422980BDBM50422980(CHEMBL269514)
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422960BDBM50422960(GW855454X | CHEMBL231184)
Affinity DataIC50: 1.58E+4nMAssay Description:Binding affinity to human EP4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed