Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50042271
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(SB-649701 | CHEMBL245568)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(SB-649701 | CHEMBL245568)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423251(CHEMBL240461)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423244(CHEMBL397395)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423250(CHEMBL395424)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(SB-649701 | CHEMBL245568)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in Th2 cells assessed as I309 mediated migration by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423259(CHEMBL395211)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423248(CHEMBL247965)
Affinity DataIC50: 251nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423256(CHEMBL443315)
Affinity DataIC50: 501nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(SB-649701 | CHEMBL245568)
Affinity DataIC50: 501nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in HUT78 cells assessed as I309-mediated migration by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423258(CHEMBL396124)
Affinity DataIC50: 631nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423254(CHEMBL247564)
Affinity DataIC50: 794nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423262(CHEMBL240462)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423260(CHEMBL247563)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423263(CHEMBL247762)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423252(CHEMBL248171)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423257(CHEMBL393411)
Affinity DataIC50: 1.59E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(SB-649701 | CHEMBL245568)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423255(CHEMBL247761)
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423249(CHEMBL396102)
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423245(CHEMBL240249)
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423261(CHEMBL248169)
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423244(CHEMBL397395)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423265(CHEMBL430012)
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423264(CHEMBL247963)
Affinity DataIC50: 7.94E+3nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423247(CHEMBL395423)
Affinity DataIC50: 1.26E+4nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423253(CHEMBL247964)
Affinity DataIC50: 1.26E+4nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed