Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50019912
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208819(2-{2,3,4-trihydroxy-5-[methyl-(3-phenylpropyl)sulf...)
Affinity DataIC50: 39nMAssay Description:Displacement of biotinylated Bim BH3 peptide from recombinant His-tagged Mcl1 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208819(2-{2,3,4-trihydroxy-5-[methyl-(3-phenylpropyl)sulf...)
Affinity DataKi:  110nMAssay Description:Displacement of FAM-Bid BH3 peptide from human recombinant Bcl2 by FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208819(2-{2,3,4-trihydroxy-5-[methyl-(3-phenylpropyl)sulf...)
Affinity DataKi:  150nMAssay Description:Displacement of FAM-Bid BH3 peptide from human Mcl1 by FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208819(2-{2,3,4-trihydroxy-5-[methyl-(3-phenylpropyl)sulf...)
Affinity DataIC50: 330nMAssay Description:Displacement of biotinylated Bim BH3 peptide from recombinant His-tagged Bcl2 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208821(2-(2,3,4-trihydroxy-5-isopropylbenzoyl)-1,2,3,4-te...)
Affinity DataKi:  590nMAssay Description:Displacement of FAM-Bid BH3 peptide from human recombinant Bcl2 by FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208819(2-{2,3,4-trihydroxy-5-[methyl-(3-phenylpropyl)sulf...)
Affinity DataKi:  638nMAssay Description:Displacement of FAM-Bak BH3 peptide from human Bcl-xL by FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208820((3,4-dihydroisoquinolin-2(1H)-yl)(2,3,4-trihydroxy...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of FAM-Bid BH3 peptide from human recombinant Bcl2 by FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208821(2-(2,3,4-trihydroxy-5-isopropylbenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of biotinylated Bim BH3 peptide from recombinant His-tagged Bcl2 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50196033(2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide | ...)
Affinity DataKi:  3.19E+4nMAssay Description:Displacement of FAM-Bid BH3 peptide from human recombinant Bcl2 by FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208820((3,4-dihydroisoquinolin-2(1H)-yl)(2,3,4-trihydroxy...)
Affinity DataIC50: 3.82E+4nMAssay Description:Displacement of biotinylated Bim BH3 peptide from recombinant His-tagged Bcl2 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed