Compile Data Set for Download or QSAR
Report error Found 114 Enz. Inhib. hit(s) with all data for entry = 2351
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19649BDBM19649((2R)-2-(cyclohexylmethyl)-N-[(2S)-4-methanesulfony...)
Affinity DataKi:  5nM ΔG°:  -49.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19655BDBM19655((2R)-2-(2-cyclopentylethyl)-N-[(2S)-3-methyl-1-{[4...)
Affinity DataKi:  11nM ΔG°:  -47.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19646BDBM19646((2R)-2-(cyclohexylmethyl)-N-[(2S)-3-methyl-1-{[4-(...)
Affinity DataKi:  11nM ΔG°:  -47.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19653BDBM19653((2R)-2-(cyclopentylmethyl)-4-(morpholin-4-yl)-4-ox...)
Affinity DataKi:  12nM ΔG°:  -47.0kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19645BDBM19645((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  13nM ΔG°:  -46.8kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19662BDBM19662((2R)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  14nM ΔG°:  -46.6kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19644BDBM19644((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  16nM ΔG°:  -46.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19647BDBM19647((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  18nM ΔG°:  -46.0kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19656BDBM19656((2R)-2-(2-cyclopentylethyl)-4-(morpholin-4-yl)-4-o...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19667BDBM19667((2S)-2-(4-chlorophenyl)-N-[(2S)-3-methyl-1-{[4-(tr...)
Affinity DataKi:  21nM ΔG°:  -45.6kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19666BDBM19666((2S)-2-(4-fluorophenyl)-N-[(2S)-3-methyl-1-{[4-(tr...)
Affinity DataKi:  24nM ΔG°:  -45.2kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19665BDBM19665((2S)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  25nM ΔG°:  -45.1kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19661BDBM19661((2R)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  27nM ΔG°:  -44.9kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19643BDBM19643((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  28nM ΔG°:  -44.8kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19651BDBM19651((2R)-2-(cyclopentylmethyl)-4-(morpholin-4-yl)-4-ox...)
Affinity DataKi:  31nM ΔG°:  -44.6kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19663BDBM19663((2S)-4-(morpholin-4-yl)-4-oxo-2-phenyl-N-[(2S)-4-p...)
Affinity DataKi:  37nM ΔG°:  -44.1kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19652BDBM19652((2R)-2-(cyclopentylmethyl)-N-[(2S)-3-methyl-1-{[4-...)
Affinity DataKi:  38nM ΔG°:  -44.1kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19670BDBM19670((2S)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  43nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19660BDBM19660((2R)-4-(morpholin-4-yl)-4-oxo-2-(2-phenylethyl)-N-...)
Affinity DataKi:  60nM ΔG°:  -42.9kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19648BDBM19648((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  62nM ΔG°:  -42.8kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19650BDBM19650((2R)-2-(cyclohexylmethyl)-N-[(2R)-4-methanesulfony...)
Affinity DataKi:  69nM ΔG°:  -42.5kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19658BDBM19658((2R)-5,5-dimethyl-2-[2-(morpholin-4-yl)-2-oxoethyl...)
Affinity DataKi:  70nM ΔG°:  -42.5kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19654BDBM19654((2R)-2-(2-cyclohexylethyl)-4-(morpholin-4-yl)-4-ox...)
Affinity DataKi:  95nM ΔG°:  -41.7kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19649BDBM19649((2R)-2-(cyclohexylmethyl)-N-[(2S)-4-methanesulfony...)
Affinity DataKi:  98nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19668BDBM19668((2S)-2-(4-methoxyphenyl)-N-[(2S)-3-methyl-1-{[4-(t...)
Affinity DataKi:  105nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19669BDBM19669((2S)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  134nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19661BDBM19661((2R)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  184nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19646BDBM19646((2R)-2-(cyclohexylmethyl)-N-[(2S)-3-methyl-1-{[4-(...)
Affinity DataKi:  193nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19642BDBM19642((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  194nM ΔG°:  -39.9kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19662BDBM19662((2R)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  197nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19653BDBM19653((2R)-2-(cyclopentylmethyl)-4-(morpholin-4-yl)-4-ox...)
Affinity DataKi:  217nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19649BDBM19649((2R)-2-(cyclohexylmethyl)-N-[(2S)-4-methanesulfony...)
Affinity DataKi:  260nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19664BDBM19664((2S)-4-(morpholin-4-yl)-4-oxo-2-phenyl-N-[(1S)-1-p...)
Affinity DataKi:  261nM ΔG°:  -39.1kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19644BDBM19644((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  267nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19645BDBM19645((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  285nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19660BDBM19660((2R)-4-(morpholin-4-yl)-4-oxo-2-(2-phenylethyl)-N-...)
Affinity DataKi:  291nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19661BDBM19661((2R)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  372nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19657BDBM19657((2R)-4,4-dimethyl-2-[2-(morpholin-4-yl)-2-oxoethyl...)
Affinity DataKi:  408nM ΔG°:  -37.9kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19645BDBM19645((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  557nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19660BDBM19660((2R)-4-(morpholin-4-yl)-4-oxo-2-(2-phenylethyl)-N-...)
Affinity DataKi:  588nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19674BDBM19674((2S)-N-[(1S)-1-cyclopropyl-2-{[4-(trifluoromethoxy...)
Affinity DataKi:  616nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19647BDBM19647((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  636nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19663BDBM19663((2S)-4-(morpholin-4-yl)-4-oxo-2-phenyl-N-[(2S)-4-p...)
Affinity DataKi:  710nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19655BDBM19655((2R)-2-(2-cyclopentylethyl)-N-[(2S)-3-methyl-1-{[4...)
Affinity DataKi:  777nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19644BDBM19644((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  907nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19646BDBM19646((2R)-2-(cyclohexylmethyl)-N-[(2S)-3-methyl-1-{[4-(...)
Affinity DataKi:  995nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19652BDBM19652((2R)-2-(cyclopentylmethyl)-N-[(2S)-3-methyl-1-{[4-...)
Affinity DataKi:  1.14E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19638BDBM19638((2R)-2-(cyclohexylmethyl)-N-{2-[(4-fluorophenyl)am...)
Affinity DataKi:  1.37E+3nM ΔG°:  -34.8kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19647BDBM19647((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  1.48E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandChemical structure of BindingDB Monomer ID 19650BDBM19650((2R)-2-(cyclohexylmethyl)-N-[(2R)-4-methanesulfony...)
Affinity DataKi:  1.52E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
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