Affinity DataKi: 0.600nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [125I][14Tyr]nociceptin FQ from human cloned NOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I][14Tyr]nociceptin FQ from human cloned NOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 123nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 125nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 127nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 132nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 134nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 135nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 144nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 147nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 148nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 162nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair