Compile Data Set for Download or QSAR
Report error Found 111 Enz. Inhib. hit(s) with all data for entry = 50020227
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211428BDBM50211428(N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211428BDBM50211428(N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211436BDBM50211436(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 13nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211424BDBM50211424(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211430BDBM50211430((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50: 14nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211436BDBM50211436(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 14nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211438BDBM50211438(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211430BDBM50211430((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50: 15nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211426BDBM50211426(2-((R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211443BDBM50211443((3S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50: 15nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211429BDBM50211429((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50: 18nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211436BDBM50211436(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 22nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211428BDBM50211428(N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 22nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211424BDBM50211424(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211429BDBM50211429((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50: 26nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211444BDBM50211444(N-(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yla...)
Affinity DataIC50: 28nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211443BDBM50211443((3S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50: 29nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211426BDBM50211426(2-((R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50: 31nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211426BDBM50211426(2-((R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50: 31nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211443BDBM50211443((3S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50: 32nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211438BDBM50211438(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50: 37nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211434BDBM50211434(ethyl 4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yla...)
Affinity DataIC50: 37nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211440BDBM50211440(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)
Affinity DataIC50: 41nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211432BDBM50211432(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 45nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211444BDBM50211444(N-(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yla...)
Affinity DataIC50: 46nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211442BDBM50211442(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211430BDBM50211430((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50: 48nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211434BDBM50211434(ethyl 4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yla...)
Affinity DataIC50: 49nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211440BDBM50211440(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)
Affinity DataIC50: 55nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211432BDBM50211432(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 57nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211424BDBM50211424(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50: 57nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211427BDBM50211427(4-(4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yla...)
Affinity DataIC50: 59nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211439BDBM50211439((3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50: 60nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211442BDBM50211442(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211446BDBM50211446(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 67nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211431BDBM50211431(4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 67nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211423BDBM50211423(4-(4-(1H-indol-1-yl)pyrimidin-2-ylamino)-N-ethylpi...)
Affinity DataIC50: 71nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211441BDBM50211441(4-(4-(1H-indol-3-yl)pyrimidin-2-ylamino)-N-ethylpi...)
Affinity DataIC50: 74nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211434BDBM50211434(ethyl 4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yla...)
Affinity DataIC50: 82nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211446BDBM50211446(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 85nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211439BDBM50211439((3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50: 88nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211431BDBM50211431(4-(5-cyano-4-(6-fluoro-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 92nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211439BDBM50211439((3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylam...)
Affinity DataIC50: 107nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211432BDBM50211432(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 120nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211436BDBM50211436(2-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 123nMAssay Description:Inhibition of CDK2 by IMAP technologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211447BDBM50211447(2-((S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50: 139nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211437BDBM50211437(3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Affinity DataIC50: 177nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211446BDBM50211446(1-(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamin...)
Affinity DataIC50: 179nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211441BDBM50211441(4-(4-(1H-indol-3-yl)pyrimidin-2-ylamino)-N-ethylpi...)
Affinity DataIC50: 245nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211445BDBM50211445(4-(4-(1H-indol-3-yl)-5-methylpyrimidin-2-ylamino)-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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