Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50020235
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099581BDBM50099581(N-[3-(4-Ethyl-benzenesulfonylamino)-2-hydroxy-inda...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211550BDBM50211550((3S,4R)-4-(N-butyl-4-ethylphenylsulfonamido)-3-hyd...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211518BDBM50211518((3S,4R)-N-ethyl-4-(4-ethylphenylsulfonamido)-3-hyd...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211521BDBM50211521(N-((3S,4R)-6-(5-amino-3-phenyl-1H-pyrazole-1-carbo...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211547BDBM50211547(N-((3R,4S)-6-((R)-2-((2,6-dimethylphenylamino)meth...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211514BDBM50211514(N-((S)-6-((S)-2-((2,6-dimethylphenylamino)methyl)p...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211525BDBM50211525((3S,4R)-4-(4-ethyl-N-(pyridin-2-ylmethyl)phenylsul...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211535BDBM50211535(rac-trans-N-(6-((S)-2-((2,6-dimethylphenylamino)me...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211537BDBM50211537((3S,4R)-4-(4-ethyl-N-neopentylphenylsulfonamido)-3...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211523BDBM50211523((3S,4R)-4-(4-ethyl-N-(pyridin-3-ylmethyl)phenylsul...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211542BDBM50211542(N-((3S,4R)-6-((R)-2-((2,6-dimethylphenylamino)meth...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211520BDBM50211520((3S,4R)-3-hydroxy-2,2-dimethyl-N-phenethyl-4-(2-(t...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211541BDBM50211541(rac-trans-N-(2-fluorobenzyl)-N-ethyl-4-(4-ethylphe...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211548BDBM50211548((3S,4R)-N-((S)-1-benzylpyrrolidin-3-yl)-N-ethyl-4-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211534BDBM50211534((3R,4S)-N-((S)-1-benzylpyrrolidin-3-yl)-N-ethyl-4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211517BDBM50211517((3S,4R)-3-hydroxy-2,2-dimethyl-N-phenethyl-4-(4-(t...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211546BDBM50211546((3S,4R)-N-((R)-1-benzylpyrrolidin-3-yl)-N-ethyl-4-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211527BDBM50211527((3R,4S)-N-((R)-1-benzylpyrrolidin-3-yl)-N-ethyl-4-...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211538BDBM50211538(4-ethyl-N-((3S,4R)-3-hydroxy-2,2-dimethyl-6-((phen...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211529BDBM50211529((3S,4R)-4-(4-ethylphenylsulfonamido)-3-hydroxy-2,2...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211533BDBM50211533((3S,4R)-4-(4-ethylphenylsulfonamido)-3-hydroxy-2,2...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211536BDBM50211536(N-((3R,4S)-6-((S)-2-((2,6-dimethylphenylamino)meth...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211544BDBM50211544((3S,4R)-4-(N-((1H-imidazol-4-yl)methyl)-4-ethylphe...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211530BDBM50211530((3S,4R)-4-(4-ethylphenylsulfonamido)-3-hydroxy-N,2...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211526BDBM50211526(N-((3S,4R)-4-(4-ethylphenylsulfonamido)-3-hydroxy-...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211519BDBM50211519((3S,4R)-4-(4-ethyl-N-isobutylphenylsulfonamido)-3-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211528BDBM50211528((3S,4R)-3-hydroxy-2,2-dimethyl-4-(3-methylphenylsu...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211515BDBM50211515((3S,4R)-3-hydroxy-2,2-dimethyl-4-(4-methylphenylsu...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211539BDBM50211539((3S,4R)-4-(4-ethylphenylsulfonamido)-3-hydroxy-2,2...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211540BDBM50211540((3R,4S)-4-(4-ethylphenylsulfonamido)-3-hydroxy-2,2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211543BDBM50211543((3S,4R)-3-hydroxy-2,2-dimethyl-N-phenethyl-4-(phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211545BDBM50211545((3S,4R)-4-(4-ethylphenylsulfonamido)-3-hydroxy-2,2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211531BDBM50211531((3S,4R)-3-hydroxy-2,2-dimethyl-4-(4-nitrophenylsul...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211516BDBM50211516((3S,4R)-4-(4-fluorophenylsulfonamido)-3-hydroxy-2,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211549BDBM50211549((3S,4R)-3-hydroxy-4-(4-methoxyphenylsulfonamido)-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211524BDBM50211524((3S,4R)-4-(4-Ethyl-benzenesulfonylamino)-3-hydroxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211532BDBM50211532((3S,4R)-N-(2-(1H-imidazol-4-yl)ethyl)-4-(4-ethylph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211522BDBM50211522((3S,4R)-4-(4-ethylphenylsulfonamido)-3-hydroxy-N-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed