Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 2750
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24170BDBM24170(3-N,3-N-diethyl-5-methyl-2-N-(thiophene-2-)-4,5,6,...)
Affinity DataIC50: 480nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24152BDBM24152(3-N,3-N-diethyl-2-N-(thiophene-2-)-4,5,6,7-tetrahy...)
Affinity DataIC50: 1.70E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24165BDBM24165(N-[3-(piperidin-1-ylcarbonyl)-4,5,6,7-tetrahydro-1...)
Affinity DataIC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24174BDBM24174(3-N,3-N-diethyl-5,5-dimethyl-2-N-(thiophene-2-)-4,...)
Affinity DataIC50: 3.10E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24179BDBM24179(N-[3-(diethylcarbamoyl)-4H,5H,7H-thieno[2,3-c]thio...)
Affinity DataIC50: 3.30E+3nMAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24173BDBM24173(N-[3-(diethylcarbamoyl)-5-methyl-4H,5H,6H-cyclopen...)
Affinity DataIC50: 3.50E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24164BDBM24164(N-[3-(pyrrolidin-1-ylcarbonyl)-4,5,6,7-tetrahydro-...)
Affinity DataIC50: 3.90E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24153BDBM24153(N-[3-(diethylcarbamoyl)-4H,5H,6H,7H,8H-cyclohepta[...)
Affinity DataIC50: 4.10E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24166BDBM24166(N-[3-(morpholin-4-ylcarbonyl)-4,5,6,7-tetrahydro-1...)
Affinity DataIC50: 4.30E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24171BDBM24171(3-N,3-N-diethyl-6-methyl-2-N-(thiophene-2-)-4,5,6,...)
Affinity DataIC50: 5.90E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24163BDBM24163(3-N,3-N-dimethyl-2-N-(thiophene-2-)-4,5,6,7-tetrah...)
Affinity DataIC50: 6.00E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24176BDBM24176(3-N,3-N,5-triethyl-2-N-(thiophene-2-)-4,5,6,7-tetr...)
Affinity DataIC50: 7.40E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24169BDBM24169(3-N,3-N-diethyl-4-methyl-2-N-(thiophene-2-)-4,5,6,...)
Affinity DataIC50: 7.50E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24172BDBM24172(N-[3-(diethylcarbamoyl)-4-methyl-4H,5H,6H-cyclopen...)
Affinity DataIC50: 8.10E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24168BDBM24168(3-N-[2-(dimethylamino)ethyl]-3-N-methyl-2-N-(thiop...)
Affinity DataIC50: 8.60E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24151BDBM24151(N-[3-(diethylcarbamoyl)-4H,5H,6H-cyclopenta[b]thio...)
Affinity DataIC50: 9.90E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24175BDBM24175(3-N,3-N-diethyl-6,6-dimethyl-2-N-(thiophene-2-)-4,...)
Affinity DataIC50: 1.20E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24154BDBM24154(3-N,3-N-diethyl-2-N-(thiophene-3-)-4,5,6,7-tetrahy...)
Affinity DataIC50: 1.30E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24156BDBM24156(N-[3-(diethylcarbamoyl)-4,5,6,7-tetrahydro-1-benzo...)
Affinity DataIC50: 1.70E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24159BDBM24159(N,N-diethyl-2-[2-(thiophen-2-yl)acetamido]-4,5,6,7...)
Affinity DataIC50: 2.00E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24150BDBM24150(3-N,3-N-diethyl-4,5-dimethyl-2-N-(thiophene-2-)thi...)
Affinity DataIC50: 2.30E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24157BDBM24157(N-[3-(diethylcarbamoyl)-4,5,6,7-tetrahydro-1-benzo...)
Affinity DataIC50: 2.30E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24178BDBM24178(3-N,3-N-diethyl-2-N-(thiophene-2-)-4H,5H,7H-thieno...)
Affinity DataIC50: 2.40E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24167BDBM24167(3-N-[2-(dimethylamino)ethyl]-2-N-(thiophene-2-)-4,...)
Affinity DataIC50: 2.70E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24158BDBM24158(2-N-benzene-3-N,3-N-diethyl-4,5,6,7-tetrahydro-1-b...)
Affinity DataIC50: 3.30E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24177BDBM24177(3-N,3-N,6-triethyl-2-N-(thiophene-2-)-4,5,6,7-tetr...)
Affinity DataIC50: 6.90E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24155BDBM24155(N-[3-(diethylcarbamoyl)-4,5,6,7-tetrahydro-1-benzo...)
Affinity DataIC50: 7.60E+4nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24180BDBM24180(3-N,3-N-diethyl-2-N-(thiophene-2-)-4H,5H,6H,7H-thi...)
Affinity DataIC50: 1.00E+5nMAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24181BDBM24181(3-N,3-N-diethyl-2-N-(thiophene-2-)-1-benzothiophen...)
Affinity DataIC50: 1.00E+5nMAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24149BDBM24149(3-N,3-N-diethyl-2-N-(thiophene-2-)thiophene-2,3-di...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24160BDBM24160(ethyl 2-(thiophene-2-amido)-4,5,6,7-tetrahydro-1-b...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24161BDBM24161(2-(thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzoth...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandChemical structure of BindingDB Monomer ID 24162BDBM24162(2-N-(thiophene-2-)-4,5,6,7-tetrahydro-1-benzothiop...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed