Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50020627
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215709BDBM50215709(CHEMBL1170 | Propionic acid 10,13-dimethyl-3-oxo-2...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18173BDBM18173(4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrro...)
Affinity DataEC50:  0.440nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215713BDBM50215713(2-chloro-4-((3aS,4R)-4-hydroxy-1,1,3-trioxo-tetrah...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18173BDBM18173(4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrro...)
Affinity DataKi:  2.11nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18171BDBM18171(hydantoin, 7 | 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hex...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215715BDBM50215715((2S,3R)-1-(3-chloro-4-cyano-2-methyl-phenylsulfamo...)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215709BDBM50215709(CHEMBL1170 | Propionic acid 10,13-dimethyl-3-oxo-2...)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18171BDBM18171(hydantoin, 7 | 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hex...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215716BDBM50215716(2-chloro-4-((3aS,4R)-4-hydroxy-3a-methyl-1,1,3-tri...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215713BDBM50215713(2-chloro-4-((3aS,4R)-4-hydroxy-1,1,3-trioxo-tetrah...)
Affinity DataEC50:  11.9nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215714BDBM50215714(2-chloro-4-((3aR,4R)-4-hydroxy-1,1-dioxo-tetrahydr...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215710BDBM50215710(2-chloro-4-((3aR,4S)-4-hydroxy-3-methyl-1,1-dioxo-...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215712BDBM50215712(2-chloro-4-((3aS,4S)-4-hydroxy-1,1,3-trioxo-tetrah...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215718BDBM50215718((2S,3R)-methyl 1-(3-chloro-4-cyano-2-methylphenyls...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215711BDBM50215711(2-chloro-4-((3aS,5S)-5-hydroxy-1,1,3-trioxo-tetrah...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215719BDBM50215719(2-chloro-4-((3aR,4S)-4-hydroxy-1,1-dioxo-tetrahydr...)
Affinity DataKi:  189nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215718BDBM50215718((2S,3R)-methyl 1-(3-chloro-4-cyano-2-methylphenyls...)
Affinity DataIC50: 278nMAssay Description:Antagonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215716BDBM50215716(2-chloro-4-((3aS,4R)-4-hydroxy-3a-methyl-1,1,3-tri...)
Affinity DataEC50:  1.25E+3nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215712BDBM50215712(2-chloro-4-((3aS,4S)-4-hydroxy-1,1,3-trioxo-tetrah...)
Affinity DataEC50:  2.96E+3nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215718BDBM50215718((2S,3R)-methyl 1-(3-chloro-4-cyano-2-methylphenyls...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215711BDBM50215711(2-chloro-4-((3aS,5S)-5-hydroxy-1,1,3-trioxo-tetrah...)
Affinity DataEC50:  3.52E+3nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215717BDBM50215717((2S,3R)-1-(3-chloro-4-cyano-2-methyl-phenylsulfamo...)
Affinity DataEC50:  7.46E+3nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215714BDBM50215714(2-chloro-4-((3aR,4R)-4-hydroxy-1,1-dioxo-tetrahydr...)
Affinity DataEC50:  7.73E+3nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215710BDBM50215710(2-chloro-4-((3aR,4S)-4-hydroxy-3-methyl-1,1-dioxo-...)
Affinity DataEC50:  8.96E+3nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed