Compile Data Set for Download or QSAR
maximum 50k data
Found 61 Enz. Inhib. hit(s) with all data for entry = 50020956
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27962(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219377(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219362(3-(2-benzyl-1-methyl-1H-benzo[d]imidazol-5-yl)-1-(...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27963(3-(2-(2-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219382(3-((1s,3s)-3-(4-methylpiperazin-1-yl)cyclobutyl)-1...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219357(3-[2-(2-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219361(3-(2-(2-fluorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27962(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...)
Affinity DataIC50:  56nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219371(3-(2-(3-fluorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219382(3-((1s,3s)-3-(4-methylpiperazin-1-yl)cyclobutyl)-1...)
Affinity DataIC50:  58nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27961(3-(2-benzyl-1H-1,3-benzodiazol-6-yl)-1-[4-(morphol...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219380(3-(2-(2-bromobenzyl)-1H-benzo[d]imidazol-5-yl)-1-(...)
Affinity DataIC50:  65nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219383(3-[2-(4-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219380(3-(2-(2-bromobenzyl)-1H-benzo[d]imidazol-5-yl)-1-(...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219355(5-(3-(benzyloxy)phenyl)-7-(3-(pyrrolidin-1-ylmethy...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219379(3-(2-(2,6-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219377(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...)
Affinity DataIC50:  84nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27963(3-(2-(2-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  90nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219367(3-(2-(2-chloro-6-fluorobenzyl)-1H-benzo[d]imidazol...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27961(3-(2-benzyl-1H-1,3-benzodiazol-6-yl)-1-[4-(morphol...)
Affinity DataIC50:  94nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219379(3-(2-(2,6-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  104nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219367(3-(2-(2-chloro-6-fluorobenzyl)-1H-benzo[d]imidazol...)
Affinity DataIC50:  113nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219357(3-[2-(2-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4...)
Affinity DataIC50:  117nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219365(3-(2-(3-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  123nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219374(3-(2-(2,6-dichlorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  125nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219362(3-(2-benzyl-1-methyl-1H-benzo[d]imidazol-5-yl)-1-(...)
Affinity DataIC50:  132nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219371(3-(2-(3-fluorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  140nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Affinity DataIC50:  142nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219363(3-(2-(3,5-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  152nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219361(3-(2-(2-fluorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  168nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219373(3-(2-(2,3-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  173nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219385(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-phenyl-1H-...)
Affinity DataIC50:  176nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219363(3-(2-(3,5-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  183nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219372(3-[2-(3-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4...)
Affinity DataIC50:  186nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219373(3-(2-(2,3-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  197nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219374(3-(2-(2,6-dichlorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  252nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219383(3-[2-(4-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4...)
Affinity DataIC50:  257nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219372(3-[2-(3-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4...)
Affinity DataIC50:  267nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219355(5-(3-(benzyloxy)phenyl)-7-(3-(pyrrolidin-1-ylmethy...)
Affinity DataIC50:  323nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219375(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-phenethyl-...)
Affinity DataIC50:  328nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219365(3-(2-(3-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  372nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219369(3-(2-(3,4-dichlorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  429nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219375(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-phenethyl-...)
Affinity DataIC50:  487nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219369(3-(2-(3,4-dichlorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  488nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219364(3-(2-(4-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  637nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219364(3-(2-(4-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  642nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219381(3-(2-(3,4-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  674nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219385(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-phenyl-1H-...)
Affinity DataIC50:  787nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219381(3-(2-(3,4-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  819nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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