Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 4678
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

LigandPNGBDBM81735(PPY-B)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1 [T315I](Human)
Ariad Pharmaceuticals

LigandPNGBDBM81735(PPY-B)
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1 [T315I](Human)
Ariad Pharmaceuticals

LigandPNGBDBM81734(PPY-A)
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

LigandPNGBDBM81734(PPY-A)
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1 [T315I](Human)
Ariad Pharmaceuticals

LigandPNGBDBM81736(PPY-C)
Affinity DataIC50: 41nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

LigandPNGBDBM81736(PPY-C)
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1 [T315I](Human)
Ariad Pharmaceuticals

LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 700nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 1.90E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1 [T315I](Human)
Ariad Pharmaceuticals

LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 3.00E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)