Compile Data Set for Download or QSAR
maximum 50k data
Found 99 Enz. Inhib. hit(s) with all data for entry = 50038917
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50:  10nMAssay Description:Inhibition of CAMKKbeta in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetAurora kinase C(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50307127((3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-I...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Aurora C in the presence of 5uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  19nMAssay Description:Inhibition of RIP2 in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50307127((3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-I...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Aurora B in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  26nMAssay Description:Inhibition of RIP2 in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50095227((6,7-Dimethoxy-quinazolin-4-yl)-(4-phenoxy-phenyl)...)
Affinity DataIC50:  26nMAssay Description:Inhibition of RIP2 in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CDK2-cyclinA in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  30nMAssay Description:Inhibition of PIM3 in the presence of 5uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  31nMAssay Description:Inhibition of Lck in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50153835(1-(3-dimethylaminophenylcarboxamido)-3-(4-hydroxyp...)
Affinity DataIC50:  31nMAssay Description:Inhibition of c-Raf in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM4811((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Aurora B in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  36nMAssay Description:Inhibition of Src in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Aurora B in the presence of 100uM ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  40nMAssay Description:Inhibition of GSK3-beta in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Lck in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  41nMAssay Description:Inhibition of CK1delta in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  53nMAssay Description:Inhibition of Src in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Aurora C in the presence of 100uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  70nMAssay Description:Inhibition of PIM2 in the presence of 5uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataIC50:  80nMAssay Description:Inhibition of DYRK1A in the presence of 50uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  80nMAssay Description:Inhibition of PIM1 in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50:  83nMAssay Description:Inhibition of PIM3 in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase BRSK2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50307127((3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-I...)
Affinity DataIC50:  100nMAssay Description:Inhibition of BRSK2 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50307127((3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-I...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Src in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  100nMAssay Description:Inhibition of PIM3 in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50307127((3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-I...)
Affinity DataIC50:  110nMAssay Description:Inhibition of MST2 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50:  110nMAssay Description:Inhibition of PIM2 in the presence of 5uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50:  120nMAssay Description:Inhibition of MNK1 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of RIP2 in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM92455(CHEMBL265470 | STO-609)
Affinity DataIC50:  120nMAssay Description:Inhibition of CAMKKalpha in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50298225(CHEMBL2069955 | CHEMBL573578 | NM-PP1 | US10544104...)
Affinity DataIC50:  130nMAssay Description:Inhibition of RIP2 in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PAK4 in the presence of 5uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50298225(CHEMBL2069955 | CHEMBL573578 | NM-PP1 | US10544104...)
Affinity DataIC50:  140nMAssay Description:Inhibition of JNK-M108G in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CDK2-cyclinA in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50307127((3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-I...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Lck in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)
Affinity DataIC50:  150nMAssay Description:Inhibition of CK1delta in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  170nMAssay Description:Inhibition of PIM1 in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  170nMAssay Description:Inhibition of c-Raf in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  170nMAssay Description:Inhibition of CK1delta in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50095227((6,7-Dimethoxy-quinazolin-4-yl)-(4-phenoxy-phenyl)...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Src in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  190nMAssay Description:Inhibition of B-Raf in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM4811((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Aurora C in the presence of 5uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50153835(1-(3-dimethylaminophenylcarboxamido)-3-(4-hydroxyp...)
Affinity DataIC50:  230nMAssay Description:Inhibition of B-Raf in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50130248(CHEMBL79004 | N-(6-Chloro-9H-beta-carbolin-8-yl)-n...)
Affinity DataIC50:  250nMAssay Description:Inhibition of IKK-beta in the presence of 5uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50298225(CHEMBL2069955 | CHEMBL573578 | NM-PP1 | US10544104...)
Affinity DataIC50:  250nMAssay Description:Inhibition of JNK-M108A in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50298225(CHEMBL2069955 | CHEMBL573578 | NM-PP1 | US10544104...)
Affinity DataIC50:  250nMAssay Description:Inhibition of PKD1 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)
Affinity DataIC50:  270nMAssay Description:Inhibition of JNK-M108A in the presence of 20uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CK1delta in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  300nMAssay Description:Inhibition of DYRK2 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)
Affinity DataIC50:  340nMAssay Description:Inhibition of Src in the presence of 50uM ATPMore data for this Ligand-Target Pair
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