Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 2533
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21702(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-indol-2-yl)carbon...)
Affinity DataEC50:  34nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3...)
Affinity DataEC50:  44nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21701(racemic mixture | 2-ethyl-1-{1-[(5-methoxy-1H-indo...)
Affinity DataEC50:  130nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21708(2-ethyl-1-[(3R)-1-[(5-ethyl-1H-indol-2-yl)carbonyl...)
Affinity DataEC50:  270nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21697(2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]pi...)
Affinity DataEC50:  690nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21706(1-[(3R)-1-[(5-bromo-1H-indol-2-yl)carbonyl]pyrroli...)
Affinity DataEC50:  810nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21698(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  830nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21696(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  1.02E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21704(2-ethyl-1-[(3R)-1-[(5-fluoro-1H-indol-2-yl)carbony...)
Affinity DataEC50:  1.49E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21699(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  1.52E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataEC50:  1.87E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21700(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  2.71E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21703(2-ethyl-1-[(3S)-1-[(5-methoxy-1H-indol-2-yl)carbon...)
Affinity DataEC50:  3.50E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21695(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  5.10E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21694(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  6.39E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21693(CHEMBL377169 | 1-(2-chlorophenyl)-3-[1-methyl-3-ox...)
Affinity DataEC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21707(2-ethyl-1-[(3R)-1-{[5-(trifluoromethoxy)-1H-indol-...)
Affinity DataEC50:  1.22E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21705(1-[(3R)-1-[(5-chloro-1H-indol-2-yl)carbonyl]pyrrol...)
Affinity DataEC50:  1.41E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed