Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50021433
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224551BDBM50224551(difluoro(4-(2-oxo-1,2-diphenylethyl)phenyl)methylp...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224541BDBM50224541(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PTP1B in a cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224541BDBM50224541(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224537BDBM50224537(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224546BDBM50224546(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224549BDBM50224549(2-(4-(4-methoxybenzyloxy)-3-(2-(2-(4-chlorophenyl)...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224543BDBM50224543(2-(4-(4-fluorobenzyloxy)-3-(2-(2-(4-chlorophenyl)-...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224536BDBM50224536(2-(1-benzyl-5-(2-(2-(4-chlorophenyl)-4-methylthiaz...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224548BDBM50224548(2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224542BDBM50224542(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224545BDBM50224545(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224550BDBM50224550(2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224547BDBM50224547(2-(3-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13990BDBM13990(CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224540BDBM50224540(3,3,3-trifluoro-2-hydroxy-2-(5-(2-(3-hydroxy-2-(me...)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224538BDBM50224538(2-(7-(benzyloxy)-1-(methoxymethyl)-1H-indol-3-yl)-...)
Affinity DataIC50: 1.76E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224539BDBM50224539(2-(6-(benzyloxy)-1-(methoxymethyl)-1H-indol-3-yl)-...)
Affinity DataIC50: 3.82E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224544BDBM50224544(2-(4-(carboxymethoxy)-3-(2-(2-(4-chlorophenyl)-4-m...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed