Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50021667
TargetCarboxypeptidase B(Pig)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201438BDBM50201438((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...)
Affinity DataKi:  0.420nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase N catalytic chain(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201438BDBM50201438((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...)
Affinity DataKi:  2nMAssay Description:Inhibition of human plasma carboxypeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201438BDBM50201438((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...)
Affinity DataKi:  4nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226610BDBM50226610((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...)
Affinity DataKi:  10nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase A1(Bovine)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50109593BDBM50109593(SQ-14603 | 2-Mercaptomethyl-3-phenyl-propionic aci...)
Affinity DataKi:  11nMAssay Description:Inhibition of bovine pancreatic carboxypeptidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226605BDBM50226605((+/-)-5-amino-2-((1-propyl-1H-imidazol-4-yl)methyl...)
Affinity DataKi:  46nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226598BDBM50226598((S)-2-(2-aminoethylamino)-3-(1-butyl-1H-imidazol-4...)
Affinity DataKi:  70nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226606BDBM50226606((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...)
Affinity DataKi:  84nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226597BDBM50226597((S)-2-(2-aminoethylamino)-3-(1-isobutyl-1H-imidazo...)
Affinity DataKi:  100nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226611BDBM50226611((S)-2-(2-aminoethylamino)-3-(1-(3-hydroxypropyl)-1...)
Affinity DataKi:  111nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226614BDBM50226614((S)-2-(2-aminoethylamino)-3-(1-(cyclobutylmethyl)-...)
Affinity DataKi:  124nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226607BDBM50226607((+/-)-2-((1H-imidazol-4-yl)methyl)-5-aminopentanoi...)
Affinity DataKi:  140nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226613BDBM50226613((S)-2-(2-aminoethylamino)-3-(1-phenethyl-1H-imidaz...)
Affinity DataKi:  140nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226602BDBM50226602((S)-2-(2-aminoethylamino)-3-(1-pentyl-1H-imidazol-...)
Affinity DataKi:  160nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Pig)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226610BDBM50226610((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...)
Affinity DataKi:  206nMAssay Description:Inhibition of porcine pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226601BDBM50226601((2S)-2-[(2-aminoethyl)amino]-3-(1-methyl-1H-imidaz...)
Affinity DataKi:  235nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226599BDBM50226599((S)-2-(2-aminoethylamino)-3-(1-ethyl-1H-imidazol-4...)
Affinity DataKi:  250nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226608BDBM50226608((S)-2-(2-aminoethylamino)-3-(1-benzyl-1H-imidazol-...)
Affinity DataKi:  269nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226603BDBM50226603((+/-)-5-amino-2-(mercaptomethyl)pentanoic acid | C...)
Affinity DataKi:  300nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226600BDBM50226600((2S)-2-[(2-aminoethyl)amino]-3-(1H-imidazol-4-yl)p...)
Affinity DataKi:  344nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226609BDBM50226609((S)-2-(2-aminoethylamino)-3-(1-isopropyl-1H-imidaz...)
Affinity DataKi:  430nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226604BDBM50226604(ent-(2S)-5-amino-2-[(1-n-propyl-1H-imidazol-4-yl)m...)
Affinity DataKi: >700nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase N catalytic chain(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226600BDBM50226600((2S)-2-[(2-aminoethyl)amino]-3-(1H-imidazol-4-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human plasma carboxypeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226612BDBM50226612((R)-2-(2-aminoethylamino)-3-(1H-imidazol-4-yl)prop...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human TAFIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed