Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 2847
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25233BDBM25233(N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-cya...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25237BDBM25237(N-(2-aminophenyl)-4-{3-cyano-5-[(4-ethylpiperazin-...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25241BDBM25241(N-(2-aminophenyl)-4-(3-cyano-5-{[4-(propan-2-yl)pi...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25231BDBM25231(N-(2-aminophenyl)-4-(3-cyanopyridin-2-yl)benzamide...)
Affinity DataIC50: 12nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25242BDBM25242(N-(2-aminophenyl)-4-(3-chloro-5-{[4-(propan-2-yl)p...)
Affinity DataIC50: 13nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25238BDBM25238(N-(2-aminophenyl)-4-{3-chloro-5-[(4-ethylpiperazin...)
Affinity DataIC50: 16nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25234BDBM25234(N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-chl...)
Affinity DataIC50: 19nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25236BDBM25236(N-(2-aminophenyl)-4-{5-[(4-ethylpiperazin-1-yl)met...)
Affinity DataIC50: 19nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25240BDBM25240(N-(2-aminophenyl)-4-(3-methyl-5-{[4-(propan-2-yl)p...)
Affinity DataIC50: 19nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25232BDBM25232(N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-met...)
Affinity DataIC50: 21nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25243BDBM25243(N-(2-aminophenyl)-4-(3-fluoro-5-{[4-(propan-2-yl)p...)
Affinity DataIC50: 33nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25239BDBM25239(N-(2-aminophenyl)-4-{5-[(4-ethylpiperazin-1-yl)met...)
Affinity DataIC50: 38nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25235BDBM25235(N-(2-aminophenyl)-4-[5-(azetidin-1-ylmethyl)-3-flu...)
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2008
Entry Details Article
PubMed