Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50026165
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataKi:  2.03nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102005(CHEMBL55780 | CHEMBL482903 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  4.11nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM25870(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
Affinity DataKi:  4.38nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(CHEMBL520301 | CHEMBL57567 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  6.46nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271564([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-6-metho...)
Affinity DataKi:  11.4nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271564([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-6-metho...)
Affinity DataKi:  13.3nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102005(CHEMBL55780 | CHEMBL482903 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  25.3nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM25870(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
Affinity DataKi:  32.8nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(CHEMBL520301 | CHEMBL57567 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  44.7nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271564([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-6-metho...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102005(CHEMBL55780 | CHEMBL482903 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(CHEMBL520301 | CHEMBL57567 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  164nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271567([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-5-methox...)
Affinity DataKi:  213nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271566([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-6-methox...)
Affinity DataKi:  374nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271566([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-6-methox...)
Affinity DataKi:  685nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271566([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-6-methox...)
Affinity DataKi:  712nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271564([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-6-metho...)
Affinity DataKi:  1.03E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271566([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-6-methox...)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271567([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-5-methox...)
Affinity DataKi:  1.12E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271567([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-5-methox...)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(CHEMBL520301 | CHEMBL57567 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102005(CHEMBL55780 | CHEMBL482903 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  1.68E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271567([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-5-methox...)
Affinity DataKi:  1.81E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271565([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-5-metho...)
Affinity DataKi:  1.91E+3nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271565([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-5-metho...)
Affinity DataKi:  1.99E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102005(CHEMBL55780 | CHEMBL482903 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  2.49E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271567([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-5-methox...)
Affinity DataKi:  2.66E+3nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271564([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-6-metho...)
Affinity DataKi:  2.77E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(CHEMBL520301 | CHEMBL57567 | 2-[3-(5-Fluoro-1H-ind...)
Affinity DataKi:  2.88E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271565([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-5-metho...)
Affinity DataKi:  2.98E+3nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271565([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-5-metho...)
Affinity DataKi:  3.49E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271566([C11]-2-[3-(5-Iodo-1H-indol-3-yl)-propyl]-6-methox...)
Affinity DataKi:  3.65E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50271565([C11]-2-[3-(5-Bromo-1H-indol-3-yl)-propyl]-5-metho...)
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed