Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 3105
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28084((4Z)-6-[(3-acetylphenyl)amino]-4-({[4-(4-methylpip...)
Affinity DataIC50: 319nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28060((4Z)-6-[(3-acetylphenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 438nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28050((4Z)-6-(phenylamino)-4-({[4-(piperidin-1-ylmethyl)...)
Affinity DataIC50: 455nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28053((4Z)-6-[(4-methylphenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 498nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28085((4Z)-4-({[4-(3,5-dimethylpiperazin-1-yl)phenyl]ami...)
Affinity DataIC50: 540nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28082((4Z)-4-[({4-[(dimethylamino)methyl]phenyl}amino)me...)
Affinity DataIC50: 566nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28054((4Z)-6-[(2-methoxyphenyl)amino]-4-({[4-(piperidin-...)
Affinity DataIC50: 610nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28079((4Z)-4-({[4-(3,5-dimethylpiperazin-1-yl)phenyl]ami...)
Affinity DataIC50: 629nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28077((4Z)-6-(furan-3-yl)-4-({[4-(piperidin-1-ylmethyl)p...)
Affinity DataIC50: 715nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28078(N-[(4Z)-4-({[4-(4-methylpiperazin-1-yl)phenyl]amin...)
Affinity DataIC50: 829nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28083((4Z)-4-[({4-[(dimethylamino)methyl]phenyl}amino)me...)
Affinity DataIC50: 887nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28075((4Z)-6-(2H-1,3-benzodioxol-5-ylamino)-4-({[4-(pipe...)
Affinity DataIC50: 894nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28080((4Z)-4-[({4-[(dimethylamino)methyl]phenyl}amino)me...)
Affinity DataIC50: 920nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28069(4-{[(4Z)-1,3-dioxo-4-({[4-(piperidin-1-ylmethyl)ph...)
Affinity DataIC50: 957nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28056((4Z)-6-[(4-methoxyphenyl)amino]-4-({[4-(piperidin-...)
Affinity DataIC50: 971nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28055((4Z)-6-[(3-methoxyphenyl)amino]-4-({[4-(piperidin-...)
Affinity DataIC50: 1.08E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28058(3-{[(4Z)-1,3-dioxo-4-({[4-(piperidin-1-ylmethyl)ph...)
Affinity DataIC50: 1.13E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28086((4Z)-4-[({4-[(diethylamino)methyl]phenyl}amino)met...)
Affinity DataIC50: 1.16E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28059(4-{[(4Z)-1,3-dioxo-4-({[4-(piperidin-1-ylmethyl)ph...)
Affinity DataIC50: 1.33E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28081((4Z)-4-[({4-[(dimethylamino)methyl]phenyl}amino)me...)
Affinity DataIC50: 1.39E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28062((4Z)-6-[(2-chlorophenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 1.66E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28063((4Z)-6-[(3-chlorophenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 2.39E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28046((4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]...)
Affinity DataIC50: 2.42E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28065((4Z)-6-[(3-fluorophenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 2.63E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28047(CHEMBL407095 | (4Z)-6-bromo-4-({[4-(piperidin-1-yl...)
Affinity DataIC50: 2.89E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28051((4Z)-6-[(2-methylphenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 4.14E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28057(2-{[(4Z)-1,3-dioxo-4-({[4-(piperidin-1-ylmethyl)ph...)
Affinity DataIC50: 4.20E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28072((4Z)-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}met...)
Affinity DataIC50: 5.20E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28061((4Z)-6-[(4-acetylphenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 5.89E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28076((4Z)-6-bromo-4-[({4-[(dimethylamino)methyl]phenyl}...)
Affinity DataIC50: 7.17E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28074((4Z)-6-(2,3-dihydro-1H-inden-5-ylamino)-4-({[4-(pi...)
Affinity DataIC50: 7.93E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28070(ethyl 4-{[(4Z)-1,3-dioxo-4-({[4-(piperidin-1-ylmet...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28071((4Z)-6-{[3-methoxy-5-(trifluoromethyl)phenyl]amino...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28073((4Z)-6-(1H-indol-5-ylamino)-4-({[4-(piperidin-1-yl...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28048((4Z)-6-[(3-chlorophenyl)amino]-4-[(phenylamino)met...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28064((4Z)-6-[(4-chlorophenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28049((4Z)-6-[(3-methoxyphenyl)amino]-4-[(phenylamino)me...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28066((4Z)-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}met...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28067((4Z)-6-[(3-aminophenyl)amino]-4-({[4-(piperidin-1-...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28052((4Z)-6-[(3-methylphenyl)amino]-4-({[4-(piperidin-1...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28068((4Z)-6-{[4-(dimethylamino)phenyl]amino}-4-({[4-(pi...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed