Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50038674
LigandPNGBDBM28365(CHEMBL512355 | N-[4-(2-cyanoethyl)cyclohexyl]-N-cy...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28365(CHEMBL512355 | N-[4-(2-cyanoethyl)cyclohexyl]-N-cy...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243635(N-((1r,4S)-4-(4-cyanophenyl)cyclohexyl)-N-cyclopro...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243632((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243595((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243633(N-cyclopropyl-N-((1r,4S)-4-phenylcyclohexyl)-4-((S...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28365(CHEMBL512355 | N-[4-(2-cyanoethyl)cyclohexyl]-N-cy...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28361(N-cyclopropyl-N-[4-(pyridin-3-yl)cyclohexyl]-4-[(2...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243595((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243672(1,1,1-trifluoro-2-(4-((S)-2-methylpiperidin-1-ylsu...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243632((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243596((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28361(N-cyclopropyl-N-[4-(pyridin-3-yl)cyclohexyl]-4-[(2...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243635(N-((1r,4S)-4-(4-cyanophenyl)cyclohexyl)-N-cyclopro...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28361(N-cyclopropyl-N-[4-(pyridin-3-yl)cyclohexyl]-4-[(2...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243634((S)-N-(cis-4-Phenyl)cyclohexyl-4-(1,1,1-trifluoro-...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243631(N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243633(N-cyclopropyl-N-((1r,4S)-4-phenylcyclohexyl)-4-((S...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28365(CHEMBL512355 | N-[4-(2-cyanoethyl)cyclohexyl]-N-cy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243635(N-((1r,4S)-4-(4-cyanophenyl)cyclohexyl)-N-cyclopro...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243633(N-cyclopropyl-N-((1r,4S)-4-phenylcyclohexyl)-4-((S...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243634((S)-N-(cis-4-Phenyl)cyclohexyl-4-(1,1,1-trifluoro-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243596((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243595((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243631(N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243632((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243634((S)-N-(cis-4-Phenyl)cyclohexyl-4-(1,1,1-trifluoro-...)
Affinity DataIC50: 123nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28361(N-cyclopropyl-N-[4-(pyridin-3-yl)cyclohexyl]-4-[(2...)
Affinity DataIC50: 124nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243633(N-cyclopropyl-N-((1r,4S)-4-phenylcyclohexyl)-4-((S...)
Affinity DataIC50: 155nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243635(N-((1r,4S)-4-(4-cyanophenyl)cyclohexyl)-N-cyclopro...)
Affinity DataIC50: 161nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243596((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 163nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243631(N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-...)
Affinity DataIC50: 849nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243632((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28365(CHEMBL512355 | N-[4-(2-cyanoethyl)cyclohexyl]-N-cy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM28361(N-cyclopropyl-N-[4-(pyridin-3-yl)cyclohexyl]-4-[(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243635(N-((1r,4S)-4-(4-cyanophenyl)cyclohexyl)-N-cyclopro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243634((S)-N-(cis-4-Phenyl)cyclohexyl-4-(1,1,1-trifluoro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243633(N-cyclopropyl-N-((1r,4S)-4-phenylcyclohexyl)-4-((S...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed