Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 2969
LigandPNGBDBM26467(3-({4-[methyl(3-methyl-1H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26477(5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylph...)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26478(6,7-dimethoxy-N-(3-methyl-1H-indazol-6-yl)quinazol...)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26470(3-({4-[(2-benzyl-3-methyl-2H-indazol-6-yl)(methyl)...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26469(3-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26476(5-({2-[(3-bromophenyl)amino]pyrimidin-4-yl}amino)-...)
Affinity DataIC50: 6.30nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26479(4-N-(3-methyl-1H-indazol-6-yl)-2-N-(3,4,5-trimetho...)
Affinity DataIC50: 6.30nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26471(3-({4-[methyl(2-methyl-2H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 7.60nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26473(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-5-yl)(meth...)
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26468(3-({4-[(1,3-dimethyl-1H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 36nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
LigandPNGBDBM26475(2-N,4-N-bis(3-bromophenyl)-5-fluoropyrimidine-2,4-...)
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gsk

LigandPNGBDBM26470(3-({4-[(2-benzyl-3-methyl-2H-indazol-6-yl)(methyl)...)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gsk

LigandPNGBDBM26467(3-({4-[methyl(3-methyl-1H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 700nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gsk

LigandPNGBDBM26468(3-({4-[(1,3-dimethyl-1H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gsk

LigandPNGBDBM26469(3-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Gsk

LigandPNGBDBM26470(3-({4-[(2-benzyl-3-methyl-2H-indazol-6-yl)(methyl)...)
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Gsk

LigandPNGBDBM26468(3-({4-[(1,3-dimethyl-1H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 1.70E+3nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50: 1.70E+3nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gsk

LigandPNGBDBM26471(3-({4-[methyl(2-methyl-2H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 2.90E+3nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Gsk

LigandPNGBDBM26471(3-({4-[methyl(2-methyl-2H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 3.90E+3nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Gsk

LigandPNGBDBM26467(3-({4-[methyl(3-methyl-1H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 4.80E+3nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Gsk

LigandPNGBDBM26468(3-({4-[(1,3-dimethyl-1H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 6.30E+3nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Gsk

LigandPNGBDBM26467(3-({4-[methyl(3-methyl-1H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 7.20E+3nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gsk

LigandPNGBDBM26473(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-5-yl)(meth...)
Affinity DataIC50: 9.00E+3nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Gsk

LigandPNGBDBM26471(3-({4-[methyl(2-methyl-2H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 9.20E+3nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Gsk

LigandPNGBDBM26468(3-({4-[(1,3-dimethyl-1H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 9.30E+3nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50: 1.50E+4nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Gsk

LigandPNGBDBM26467(3-({4-[methyl(3-methyl-1H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 1.60E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Gsk

LigandPNGBDBM26469(3-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 1.60E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Gsk

LigandPNGBDBM26471(3-({4-[methyl(2-methyl-2H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50: 1.80E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Gsk

LigandPNGBDBM26469(3-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50: 2.50E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50: 2.60E+4nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Gsk

LigandPNGBDBM26469(3-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50: 3.10E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Gsk

LigandPNGBDBM26473(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-5-yl)(meth...)
Affinity DataIC50: 3.30E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Gsk

LigandPNGBDBM26473(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-5-yl)(meth...)
Affinity DataIC50: 3.30E+4nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Gsk

LigandPNGBDBM26473(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-5-yl)(meth...)
Affinity DataIC50: 4.50E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Gsk

LigandPNGBDBM26470(3-({4-[(2-benzyl-3-methyl-2H-indazol-6-yl)(methyl)...)
Affinity DataIC50: 6.60E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Gsk

LigandPNGBDBM26470(3-({4-[(2-benzyl-3-methyl-2H-indazol-6-yl)(methyl)...)
Affinity DataIC50: 7.90E+4nMAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed