Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50038643
TargetMu-type opioid receptor(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  7.44nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262557((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  7.99nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50244419((4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a...)
Affinity DataKi:  15.1nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262557((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  23.2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  27nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  30.4nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261726((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261791((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50244419((4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a...)
Affinity DataKi:  60.6nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261726((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261791((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262499(22-cyclopropylmethyl-16-methoxy-(2S,13R)-14-oxa-11...)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50245093((5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  3.29E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261727((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  3.34E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261727((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50245093((5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262556((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262499(22-cyclopropylmethyl-16-methoxy-(2S,13R)-14-oxa-11...)
Affinity DataKi:  3.91E+3nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262556((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  4.65E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed