Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 2790
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24663BDBM24663(2-(1H-imidazol-4-yl)phenol | 2-(1H-imidazol-4-yl)p...)
Affinity DataKi:  8.90E+3nM ΔG°:  -30.0kJ/mole IC50: 4.80E+3nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24666BDBM24666(4-(1H-imidazol-4-yl)benzene-1-thiol | 4-(1H-imidaz...)
Affinity DataKi:  4.80E+3nM ΔG°:  -31.6kJ/mole IC50: 7.70E+3nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24664BDBM24664(2-(1H-imidazol-4-yl)benzene-1,3-diol | 2-(1H-imida...)
Affinity DataIC50: 5.30E+3nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24665BDBM24665(3-(1H-imidazol-4-yl)benzene-1-thiol | 3-(1H-imidaz...)
Affinity DataKi:  5.30E+3nM ΔG°:  -31.3kJ/mole IC50: 7.60E+3nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24667BDBM24667(2-(1H-imidazol-4-yl)benzene-1-thiol | 2-(1H-imidaz...)
Affinity DataIC50: 2.50E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24678BDBM24678(4-fluoro-2-(1H-pyrazol-3-yl)phenol | pyrazole, 31)
Affinity DataIC50: 2.60E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24655BDBM24655(1-benzyl-5-phenyl-1H-imidazole | 4-phenylimidazole...)
Affinity DataIC50: 3.20E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24679BDBM24679((6Z)-6-(3-pyrazolin-3-ylidene)cyclohexa-2,4-dien-1...)
Affinity DataIC50: 3.50E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24668BDBM24668(4-[2-(methylsulfanyl)phenyl]-1H-imidazole | 4-[2-(...)
Affinity DataIC50: 3.80E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24669BDBM24669(3-(1H-imidazol-4-yl)benzonitrile | 3-(1H-imidazol-...)
Affinity DataIC50: 4.10E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24656BDBM24656(CHEMBL14145 | 4-phenyl-1H-imidazole | 4-Phenylimid...)
Affinity DataIC50: 4.80E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24683BDBM24683(4-(3-fluorophenyl)-1H-imidazole | 4-(3-fluoropheny...)
Affinity DataIC50: 6.00E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24670BDBM24670(4-[3-(methylsulfanyl)phenyl]-1H-imidazole | 4-[3-(...)
Affinity DataIC50: 7.30E+4nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24671BDBM24671(4-(4-fluorophenyl)-1H-imidazole | 5-(4-fluoropheny...)
Affinity DataIC50: 1.23E+5nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24680BDBM24680(3-phenylpyridine | 3-phenylpyridine, 33)
Affinity DataIC50: 1.61E+5nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24672BDBM24672(4-(2-fluorophenyl)-1H-imidazole | 4-(2-fluoropheny...)
Affinity DataIC50: 1.79E+5nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24673BDBM24673(4-[4-(methylsulfanyl)phenyl]-1H-imidazole | 4-[4-(...)
Affinity DataIC50: 2.09E+5nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24674BDBM24674(3-(1H-imidazol-4-yl)phenol | 3-(1H-imidazol-4-yl)p...)
Affinity DataIC50: 3.65E+5nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24681BDBM24681(4-(thiophen-2-yl)-1H-imidazole | 4-thiophen-2-yl-1...)
Affinity DataIC50: 4.22E+5nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24675BDBM24675(4-(2,6-dimethoxyphenyl)-1H-imidazole | 4-(2,6-dime...)
Affinity DataIC50: 7.34E+5nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24676BDBM24676(3-(1H-imidazol-4-yl)benzaldehyde | 3-(1H-imidazol-...)
Affinity DataIC50: 8.25E+5nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24677BDBM24677(4-(1H-imidazol-4-yl)phenol | 4-(1H-imidazol-4-yl)p...)
Affinity DataIC50: 1.20E+6nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 12357BDBM12357(CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...)
Affinity DataAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24684BDBM24684(3-(furan-2-yl)pyridine | 3-furan-2-ylpyridine, 36)
Affinity DataAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24657BDBM24657(1-methyl-4-phenyl-1H-imidazole | 4-phenylimidazole...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24658BDBM24658(1-benzyl-4-phenyl-1H-imidazole | 4-phenylimidazole...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24659BDBM24659(2-(4-phenyl-1H-imidazol-1-yl)ethan-1-amine | 4-phe...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24660BDBM24660(3-(4-phenyl-1H-imidazol-1-yl)propan-1-amine | 4-ph...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24661BDBM24661((4-phenyl-1H-imidazol-2-yl)methanol | 4-phenylimid...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24662BDBM24662(methyl[(4-phenyl-1H-imidazol-2-yl)methyl]amine | 4...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 24682BDBM24682(5-phenyl-1,3-thiazole | 5-phenyl-1,3-thiazole, 34)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandChemical structure of BindingDB Monomer ID 16215BDBM16215(CHEMBL390066 | JMC514968 Compound 35 | 4-phenyl-1H...)
Affinity DatapH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed