Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50026806
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272209(1-((9H-Fluoren-2-yl)ethyl)-1H-imidazole | CHEMBL50...)
Affinity DataIC50:  4nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272156(7-(1-(1H-imidazol-1-yl)ethyl)-9H-fluoren-2-ol | CH...)
Affinity DataIC50:  99nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272209(1-((9H-Fluoren-2-yl)ethyl)-1H-imidazole | CHEMBL50...)
Affinity DataIC50:  112nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272212(2-(1-(1H-Imidazol-1-yl)ethyl)-7-fluoro-9H-carbazol...)
Affinity DataIC50:  118nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272210(1-[1-(7-Fluoro-9H-fluoren-2-yl)-ethyl]-1H-imidazol...)
Affinity DataIC50:  168nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272211(2-(1-Imidazol-1-yl-ethyl)-9H-carbazole | CHEMBL499...)
Affinity DataIC50:  282nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272542(1-(1-Biphenyl-4-yl-pentyl)-1H-imidazole | CHEMBL49...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272541(1-(1-Biphenyl-4-yl-2-methyl-propyl)-1H-imidazole |...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272068(1-[1-(4'-Fluoro-biphenyl-4-yl)-propyl]-1H-imidazol...)
Affinity DataIC50:  345nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272067(4'-(1H -Imidazol-1-yl-propyl)-biphenyl-4-ol | CHEM...)
Affinity DataIC50:  375nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272157(1-((9H-Fluoren-2-yl)methyl)-1H-imidazole | CHEMBL5...)
Affinity DataIC50:  388nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272507(1-(1-Biphenyl-4-yl-propyl)-1H-imidazole | CHEMBL49...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272544(1-(1-Biphenyl-4-yl-2,2-dimethyl-propyl)-1H-imidazo...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272540(1-(1-Biphenyl-4-yl-butyl)-1H-imidazole | CHEMBL449...)
Affinity DataIC50:  580nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272153(1-(3-Chloro-1-(4'-fluorobiphenyl-4-yl)propyl)-1H-i...)
Affinity DataIC50:  756nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272561(1-(1-Biphenyl-4-yl-2-phenyl-ethyl)-1H-imidazole | ...)
Affinity DataIC50:  780nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50128548(1-(1-Biphenyl-4-yl-2-phenyl-methyl)-1H-imidazole |...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272506(1-(1-Biphenyl-4-yl-ethyl)-1H-imidazole | CHEMBL497...)
Affinity DataIC50:  910nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272545(1-(1-Biphenyl-4-yl-cyclohexyl-methyl)-1H-imidazole...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272263(1-[1-(4'-Fluoro-biphenyl-4-yl)-ethyl]-1H-imidazole...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272100(1-(3-(4'-Fluorobiphenyl-4-yl)pentan-3-yl)-1H-imida...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272155(1-(1-(Biphenyl-4-yl)allyl)-1H-imidazole | CHEMBL44...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272065(CHEMBL500679 | [4'-(1H-Imidazol-1-yl-propyl)-biphe...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272583(1-(1-(4'-Ethylbiphenyl-4-yl)propyl)-1H-imidazole |...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272543(1-(1-Biphenyl-4-yl-3-methyl-butyl)-1H-imidazole | ...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272064(4-[4'-(1H-Imidazol-1-yl-propyl)-biphenyl-4-yl]-mor...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272562(1-(Bis-biphenyl-4-yl-methyl)-1H-imidazole | CHEMBL...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272580(1-(1-(4'-(Methylsulfanyl)biphenyl-4-yl)propyl)-1H-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272069(1-(2-(4'-Fluorobiphenyl-4-yl)propan-2-yl)-1H-imida...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272564(1-(1-(4'-(Trifluoromethoxy)biphenyl-4-yl)propyl)-1...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272582(1-(1-(4'-Methylbiphenyl-4-yl)propyl)-1H-imidazole ...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272154(1-(1-(4'-Fluorobiphenyl-4-yl)allyl)-1H-imidazole |...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272584(CHEMBL503503 | [4'-(1H-Imidazol-1-yl-propyl)-biphe...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272585(CHEMBL496258 | Diethyl-[4'-(1H-imidazol-1-yl-propy...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272581(4'-(1-(1H-Imidazol-1-yl)propyl)biphenyl-4-carbonit...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272066(CHEMBL526722 | N-[4'-(1H-Imidazol-1-yl-propyl)-bip...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272563(1-((4'-(Trifluoromethyl)biphenyl-4-yl)methyl)-1H-i...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272152(3-(4'-Fluorobiphenyl-4-yl)-3-(1H-imidazol-1-yl)pro...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed