Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50026885
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245034(N-(3,4-Difluorophenyl)-6,7-dimethoxy-2-(4-pyrrolid...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245069(N-(4-Fluorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245071(3-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245072(4-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50: 61nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245034(N-(3,4-Difluorophenyl)-6,7-dimethoxy-2-(4-pyrrolid...)
Affinity DataIC50: 69nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 70nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245112(N-(4-Chlorophenyl)-2-{4-[2-(diethylamino)ethyl]-1,...)
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245070(2-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245114(N-(4-Chlorophenyl)-6,7-dimethoxy-2-[4-(2-piperidin...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 150nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245113(N-(4-Chlorophenyl)-6,7-dimethoxy-2-[4-(2-pyrrolidi...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 200nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245035(N-(3-Bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-...)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245071(3-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245069(N-(4-Fluorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245072(4-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50: 360nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245035(N-(3-Bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-...)
Affinity DataIC50: 510nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245111(N-(4-Chlorophenyl)-2-(4-cyclohexyl-1,4-diazepan-1-...)
Affinity DataIC50: 550nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245069(N-(4-Fluorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 710nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245034(N-(3,4-Difluorophenyl)-6,7-dimethoxy-2-(4-pyrrolid...)
Affinity DataIC50: 820nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed