Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50026983
LigandPNGBDBM50264392(N-(6-acetamidopyridin-3-yl)-6-chloro-3-(3-(trifluo...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264437(N-(2-aminopyrimidin-5-yl)-6-chloro-3-(3-(trifluoro...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264391(N-(6-aminopyridin-3-yl)-6-chloro-3-(3-(trifluorome...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264389(6-chloro-N-(pyrimidin-5-yl)-3-(3-(trifluoromethyl)...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264439(6-chloro-N-(pyridin-3-yl)-3-(3-(trifluoromethyl)ph...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264389(6-chloro-N-(pyrimidin-5-yl)-3-(3-(trifluoromethyl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264363(6-chloro-N-(pyrimidin-5-yl)-3-(3-(trifluoromethoxy...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264438(N-(2-acetamidopyrimidin-5-yl)-6-chloro-3-(3-(trifl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264361(3-(3-tert-butylphenylamino)-6-chloro-N-(pyrimidin-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264291(6-chloro-3-(4-ethylphenylamino)-N-(pyrimidin-5-yl)...)
Affinity DataIC50: 7nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264292(6-chloro-3-(4-propylphenylamino)-N-(pyrimidin-5-yl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264322(3-(4-tert-butylphenylamino)-6-chloro-N-(pyrimidin-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264390(6-chloro-3-(4-fluoro-3-(trifluoromethyl)phenylamin...)
Affinity DataIC50: 11nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264360(6-chloro-N-(pyrimidin-5-yl)-3-(4-(trifluoromethoxy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264323(6-chloro-N-(pyrimidin-5-yl)-3-(4-(trifluoromethyl)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM26373(CHEMBL259247 | 4-methyl-3-N-(pyrimidin-5-yl)-1-N-[...)
Affinity DataIC50: 14nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264440(6-chloro-N-(2-chloropyrimidin-5-yl)-3-(3-(trifluor...)
Affinity DataIC50: 20nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264320(3-(4-butylphenylamino)-6-chloro-N-(pyrimidin-5-yl)...)
Affinity DataIC50: 28nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 58nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264362(6-chloro-3-(3-cyanophenylamino)-N-(pyrimidin-5-yl)...)
Affinity DataIC50: 59nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264389(6-chloro-N-(pyrimidin-5-yl)-3-(3-(trifluoromethyl)...)
Affinity DataIC50: 71nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50264389(6-chloro-N-(pyrimidin-5-yl)-3-(3-(trifluoromethyl)...)
Affinity DataIC50: 75nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264389(6-chloro-N-(pyrimidin-5-yl)-3-(3-(trifluoromethyl)...)
Affinity DataIC50: 117nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264321(6-chloro-3-(4-pentylphenylamino)-N-(pyrimidin-5-yl...)
Affinity DataIC50: 170nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264389(6-chloro-N-(pyrimidin-5-yl)-3-(3-(trifluoromethyl)...)
Affinity DataIC50: 353nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50264389(6-chloro-N-(pyrimidin-5-yl)-3-(3-(trifluoromethyl)...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed