Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50027012
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247048(CHEMBL462609 | methyl icosylphosphonofluoridate)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247049(CHEMBL462610 | ethyl 3,5,6-trichloropyridin-2-yl d...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247052(2-Nonylsulfanyl-4H-benzo[1,3,2]dioxaphosphinine 2-...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247051(CHEMBL512224 | isopropyl 4-nitrophenyl dodecylphos...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247052(2-Nonylsulfanyl-4H-benzo[1,3,2]dioxaphosphinine 2-...)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247008(CHEMBL499569 | octane-1-sulfonyl fluoride)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132715(CHEMBL97038 | Dodecanesulfonyl fluoride | dodecane...)
Affinity DataIC50:  2nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247048(CHEMBL462609 | methyl icosylphosphonofluoridate)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247086(CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247051(CHEMBL512224 | isopropyl 4-nitrophenyl dodecylphos...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132715(CHEMBL97038 | Dodecanesulfonyl fluoride | dodecane...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247086(CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247086(CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50:  12nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247051(CHEMBL512224 | isopropyl 4-nitrophenyl dodecylphos...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247049(CHEMBL462610 | ethyl 3,5,6-trichloropyridin-2-yl d...)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247048(CHEMBL462609 | methyl icosylphosphonofluoridate)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247086(CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...)
Affinity DataIC50:  40nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247049(CHEMBL462610 | ethyl 3,5,6-trichloropyridin-2-yl d...)
Affinity DataIC50:  42nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247050(4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...)
Affinity DataIC50:  70nMAssay Description:Inhibition of MAGL-mediated [14C]1-oleoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247008(CHEMBL499569 | octane-1-sulfonyl fluoride)
Affinity DataIC50:  140nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132715(CHEMBL97038 | Dodecanesulfonyl fluoride | dodecane...)
Affinity DataIC50:  200nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  540nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247008(CHEMBL499569 | octane-1-sulfonyl fluoride)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50240416(CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247086(CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...)
Affinity DataIC50:  2.50E+4nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptor expressed in HEK293 cells in presence of mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50247086(CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...)
Affinity DataKd:  0.860nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brain at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of California

Curated by ChEMBL
LigandPNGBDBM50132717(CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at CB1 receptor in mouse brain membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed