Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 2849
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25256BDBM25256(hydrogen [2-(dodecyldimethylphosphanylium)-1-phosp...)
Affinity DataIC50: 100nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25258BDBM25258(3-(decyloxy)-5-(2-hydrogen phosphonato-2-phosphono...)
Affinity DataIC50: 280nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25259BDBM25259(Bisphpshonate-715 | 3-(decyloxy)-1-(2-hydrogen pho...)
Affinity DataIC50: 280nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25260BDBM25260({2-[dodecyl(methyl)amino]-1-phosphonoethyl}phospho...)
Affinity DataIC50: 350nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25261BDBM25261(3-decyl-1-(2-hydrogen phosphonato-2-phosphonoethyl...)
Affinity DataIC50: 400nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25262BDBM25262(3-bromo-5-(decyloxy)-1-(2-hydrogen phosphonato-2-p...)
Affinity DataIC50: 510nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25263BDBM25263({2-[3-(decyloxy)phenyl]-1-hydroxy-1-phosphonoethyl...)
Affinity DataIC50: 590nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25264BDBM25264(1-(2-hydrogen phosphonato-2-phosphonoethyl)-4-octy...)
Affinity DataIC50: 660nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25265BDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)
Affinity DataIC50: 710nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25266BDBM25266({1-hydroxy-2-[3-(4-phenylphenyl)phenyl]-1-phosphon...)
Affinity DataIC50: 720nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25267BDBM25267(3-(decyloxy)-5-(3,5-difluorophenyl)-1-(2-hydrogen ...)
Affinity DataIC50: 760nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25268BDBM25268(hydrogen {2-[dimethyl(octyl)phosphanylium]-1-phosp...)
Affinity DataIC50: 890nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25269BDBM25269((1-hydroxy-1-phosphonodecyl)phosphonic acid | CHEM...)
Affinity DataIC50: 890nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25270BDBM25270([(6E,11E)-2,6,12,16-tetramethyl-9-phosphonoheptade...)
Affinity DataIC50: 980nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25271BDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)
Affinity DataIC50: 1.15E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25272BDBM25272(hydrogen {2-[dodecyl(methyl)sulfanylium]-1-phospho...)
Affinity DataIC50: 1.23E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25273BDBM25273(3-(decylamino)-1-(2-hydrogen phosphonato-2-phospho...)
Affinity DataIC50: 1.26E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25274BDBM25274(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)
Affinity DataIC50: 1.38E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25275BDBM25275(CHEMBL237808 | hydrogen {2-[methyl(tetradecyl)sulf...)
Affinity DataIC50: 1.48E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25276BDBM25276(1-(2-hydrogen phosphonato-2-phosphonoethyl)-3-(oct...)
Affinity DataIC50: 1.74E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25277BDBM25277([(6E,11E)-9-phosphonoheptadeca-6,11-dien-9-yl]phos...)
Affinity DataIC50: 1.86E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25279BDBM25279({1-hydroxy-2-[3-(3-phenylphenyl)phenyl]-1-phosphon...)
Affinity DataIC50: 2.14E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25278BDBM25278(3-(heptyloxy)-5-(2-hydrogen phosphonato-2-phosphon...)
Affinity DataIC50: 2.14E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25280BDBM25280({1-[3-(decyloxy)phenyl]-2-phosphonodecan-2-yl}phos...)
Affinity DataIC50: 2.34E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25281BDBM25281((9-phosphonoheptadecan-9-yl)phosphonic acid | bisp...)
Affinity DataIC50: 2.51E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25282BDBM25282(1-(2-hydrogen phosphonato-2-phosphonoethyl)-3-(oct...)
Affinity DataIC50: 2.51E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25283BDBM25283(3-(3-butoxyphenyl)-1-(2-hydrogen phosphonato-2-pho...)
Affinity DataIC50: 2.51E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25284BDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)
Affinity DataIC50: 2.69E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25285BDBM25285(CHEMBL416301 | (1-hydroxy-1-phosphonododecyl)phosp...)
Affinity DataIC50: 2.69E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25286BDBM25286(3-(dodecyloxy)-1-(2-hydrogen phosphonato-2-phospho...)
Affinity DataIC50: 3.02E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25287BDBM25287(hydrogen {2-[methyl(octyl)sulfanylium]-1-phosphono...)
Affinity DataIC50: 3.24E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25288BDBM25288([1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50: 3.98E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25289BDBM25289({1-hydroxy-2-[3-(3-phenylphenyl)phenoxy]-1-phospho...)
Affinity DataIC50: 4.07E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25290BDBM25290({1-hydroxy-3-[methyl(4-phenylbutyl)amino]-1-phosph...)
Affinity DataIC50: 4.17E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25291BDBM25291({2-[5-(decyloxy)pyridin-3-yl]-1-phosphonoethyl}pho...)
Affinity DataIC50: 4.57E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25292BDBM25292({2-[5-(dodecyloxy)pyridin-3-yl]-1-phosphonoethyl}p...)
Affinity DataIC50: 5.01E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25293BDBM25293(3-hexyl-1-(2-hydrogen phosphonato-2-phosphonoethyl...)
Affinity DataIC50: 6.31E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25294BDBM25294(hydrogen {2-[methyl(pentyl)sulfanylium]-1-phosphon...)
Affinity DataIC50: 8.71E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25295BDBM25295(3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-1-(2-hydro...)
Affinity DataIC50: 8.91E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25296BDBM25296(1-(2-hydrogen phosphonato-2-phosphonoethyl)-3-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25297BDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)
Affinity DataIC50: 1.12E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25298BDBM25298(CHEMBL55264 | (1-hydroxy-1-phosphonoheptyl)phospho...)
Affinity DataIC50: 1.12E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25299BDBM25299(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)
Affinity DataIC50: 1.41E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25300BDBM25300([1,3-bis(2,4-dichlorophenyl)-2-phosphonopropan-2-y...)
Affinity DataIC50: 2.75E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25301BDBM25301(1-(2-hydrogen phosphonato-2-phosphonoethyl)-3-meth...)
Affinity DataIC50: 5.37E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25302BDBM25302(CHEMBL277580 | hydrogen [2-(dimethylsulfanylium)-1...)
Affinity DataIC50: 6.61E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25303BDBM25303(CHEMBL235059 | hydrogen {2-[methyl(propyl)sulfanyl...)
Affinity DataIC50: 6.61E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25304BDBM25304((2-carbamimidamido-1-hydroxy-1-phosphonoethyl)phos...)
Affinity DataIC50: 7.41E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 25305BDBM25305(hydrogen {2-[(10-carboxydecyl)(methyl)sulfanylium]...)
Affinity DataIC50: 7.94E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandChemical structure of BindingDB Monomer ID 12577BDBM12577({1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonoprop...)
Affinity DataIC50: 7.94E+4nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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