Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50027651
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231358(1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  0.120nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  0.150nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255006(1-((5R,6S)-6-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  0.230nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231358(1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl...)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255042(1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4...)
Affinity DataIC50:  0.370nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255042(1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4...)
Affinity DataIC50:  0.370nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254448(1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methy...)
Affinity DataIC50:  0.470nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254448(1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methy...)
Affinity DataIC50:  0.470nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255070(1-(5-acetyl-4-methylthiazol-2-yl)-3-(6-(((S)-3-(4-...)
Affinity DataIC50:  1.10nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50209984(1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50163634(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  2nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255038(1-((5R,6S)-6-((cyclopropyl(3-(4-fluorophenyl)propy...)
Affinity DataIC50:  2.10nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255042(1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4...)
Affinity DataIC50:  5.40nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluo...)
Affinity DataIC50:  5.5nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluo...)
Affinity DataIC50:  5.5nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255039(1-((5R,6S)-6-(((3-(4-fluorophenyl)propyl)(propyl)a...)
Affinity DataIC50:  9.20nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50163634(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255042(1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255006(1-((5R,6S)-6-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254448(1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methy...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254448(1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methy...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50209984(1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of human ERG by calcium-flux based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255070(1-(5-acetyl-4-methylthiazol-2-yl)-3-(6-(((S)-3-(4-...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254447(1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluo...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed