Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 3292
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30538BDBM30538(5,6-Dihydro-1H-pyridin-2-one, 4aj)
Affinity DataIC50: 10nM EC50:  9nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30542BDBM30542(5,6-Dihydro-1H-pyridin-2-one, 4an)
Affinity DataIC50: 10nM EC50:  34nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30543BDBM30543(5,6-Dihydro-1H-pyridin-2-one, 4ao)
Affinity DataIC50: 10nM EC50:  45nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30544BDBM30544(5,6-Dihydro-1H-pyridin-2-one, 4ap)
Affinity DataIC50: 10nM EC50:  55nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30530BDBM30530(5,6-Dihydro-1H-pyridin-2-one, 4ad)
Affinity DataIC50: 10nM EC50:  16nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30516BDBM30516(5,6-Dihydro-1H-pyridin-2-one, 4p)
Affinity DataIC50: 10nM EC50:  60nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30418BDBM30418(BMCL19451 Compound 2 | BMCL185002 Compound 3a | py...)
Affinity DataIC50: 10nM EC50:  12nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30452BDBM30452(Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3 | hexah...)
Affinity DataIC50: 10nM EC50:  34nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30504BDBM30504(5,6-Dihydro-1H-pyridin-2-one, 4d)
Affinity DataIC50: 10nM EC50:  23nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30537BDBM30537(5,6-Dihydro-1H-pyridin-2-one, 4ai)
Affinity DataIC50: 10nM EC50:  32nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30508BDBM30508(5,6-Dihydro-1H-pyridin-2-one, 4h)
Affinity DataIC50: 10nM EC50:  24nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30541BDBM30541(5,6-Dihydro-1H-pyridin-2-one, 4am)
Affinity DataIC50: 10nM EC50:  160nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30523BDBM30523(5,6-Dihydro-1H-pyridin-2-one, 4w)
Affinity DataIC50: 20nM EC50:  170nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30510BDBM30510(5,6-Dihydro-1H-pyridin-2-one, 4j)
Affinity DataIC50: 39nM EC50:  22nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30505BDBM30505(5,6-Dihydro-1H-pyridin-2-one, 4e)
Affinity DataIC50: 22nM EC50:  150nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30418BDBM30418(BMCL19451 Compound 2 | BMCL185002 Compound 3a | py...)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30452BDBM30452(Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3 | hexah...)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30516BDBM30516(5,6-Dihydro-1H-pyridin-2-one, 4p)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30538BDBM30538(5,6-Dihydro-1H-pyridin-2-one, 4aj)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30530BDBM30530(5,6-Dihydro-1H-pyridin-2-one, 4ad)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30504BDBM30504(5,6-Dihydro-1H-pyridin-2-one, 4d)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30508BDBM30508(5,6-Dihydro-1H-pyridin-2-one, 4h)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30531BDBM30531(5,6-Dihydro-1H-pyridin-2-one, 4ae)
Affinity DataIC50: 26nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30534BDBM30534(5,6-Dihydro-1H-pyridin-2-one, 4af)
Affinity DataIC50: 27nM EC50:  120nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30542BDBM30542(5,6-Dihydro-1H-pyridin-2-one, 4an)
Affinity DataIC50: 28nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30544BDBM30544(5,6-Dihydro-1H-pyridin-2-one, 4ap)
Affinity DataIC50: 28nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30522BDBM30522(5,6-Dihydro-1H-pyridin-2-one, 4v)
Affinity DataIC50: 28nM EC50:  880nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30543BDBM30543(5,6-Dihydro-1H-pyridin-2-one, 4ao)
Affinity DataIC50: 29nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30531BDBM30531(5,6-Dihydro-1H-pyridin-2-one, 4ae)
Affinity DataIC50: 31nM EC50:  220nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30509BDBM30509(5,6-Dihydro-1H-pyridin-2-one, 4i)
Affinity DataIC50: 43nM EC50:  33nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30517BDBM30517(5,6-Dihydro-1H-pyridin-2-one, 4q)
Affinity DataIC50: 35nM EC50:  120nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30528BDBM30528(5,6-Dihydro-1H-pyridin-2-one, 4ab)
Affinity DataIC50: 40nM EC50:  39nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30506BDBM30506(5,6-Dihydro-1H-pyridin-2-one, 4f)
Affinity DataIC50: 42nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30535BDBM30535(5,6-Dihydro-1H-pyridin-2-one, 4ag)
Affinity DataIC50: 43nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30521BDBM30521(5,6-Dihydro-1H-pyridin-2-one, 4u)
Affinity DataIC50: 46nM EC50:  100nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30535BDBM30535(5,6-Dihydro-1H-pyridin-2-one, 4ag)
Affinity DataIC50: 47nM EC50:  350nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30528BDBM30528(5,6-Dihydro-1H-pyridin-2-one, 4ab)
Affinity DataIC50: 47nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30517BDBM30517(5,6-Dihydro-1H-pyridin-2-one, 4q)
Affinity DataIC50: 51nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30515BDBM30515(5,6-Dihydro-1H-pyridin-2-one, 4o)
Affinity DataIC50: 51nM EC50:  700nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30537BDBM30537(5,6-Dihydro-1H-pyridin-2-one, 4ai)
Affinity DataIC50: 51nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30506BDBM30506(5,6-Dihydro-1H-pyridin-2-one, 4f)
Affinity DataIC50: 57nM EC50:  74nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30534BDBM30534(5,6-Dihydro-1H-pyridin-2-one, 4af)
Affinity DataIC50: 63nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30509BDBM30509(5,6-Dihydro-1H-pyridin-2-one, 4i)
Affinity DataIC50: 66nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30510BDBM30510(5,6-Dihydro-1H-pyridin-2-one, 4j)
Affinity DataIC50: 73nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30541BDBM30541(5,6-Dihydro-1H-pyridin-2-one, 4am)
Affinity DataIC50: 74nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30521BDBM30521(5,6-Dihydro-1H-pyridin-2-one, 4u)
Affinity DataIC50: 99nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30525BDBM30525(5,6-Dihydro-1H-pyridin-2-one, 4y)
Affinity DataIC50: 120nM EC50:  3.10E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30523BDBM30523(5,6-Dihydro-1H-pyridin-2-one, 4w)
Affinity DataIC50: 130nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30507BDBM30507(5,6-Dihydro-1H-pyridin-2-one, 4g)
Affinity DataIC50: 130nM EC50:  7.30E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30525BDBM30525(5,6-Dihydro-1H-pyridin-2-one, 4y)
Affinity DataIC50: 190nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 66 total ) | Next | Last >>
Jump to: