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Found 31 Enz. Inhib. hit(s) with all data for entry = 50027912
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50095997(3',4',7-trihydroxyisoflavone | CHEMBL13486)
Affinity DataKi:  38nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50096003(7-Hydroxy-3-phenyl-chromen-2-one | 7-hydroxy-3-phe...)
Affinity DataKi:  470nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50096001(7-Hydroxy-3-pyrazolo[1,5-a]pyridin-2-yl-chromen-2-...)
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265450(2-oxo-2-phenylethyl 7-hydroxy-2-oxo-2H-chromene-3-...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50096006(7-Hydroxy-3-(2-methyl-thiazol-4-yl)-chromen-2-one ...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50096008(3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50095995(7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL E...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265523(3-benzyl-5-methylbenzo[d]oxazol-2(3H)-one | CHEMBL...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265470((R)-tert-butyl 2-(3-(3-fluoro-4-hydroxyphenyl)-4,5...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265523(3-benzyl-5-methylbenzo[d]oxazol-2(3H)-one | CHEMBL...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113768((S)-methyl 2-(4-hydroxybenzylideneamino)-3-(1H-ind...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265488(7-((3-fluorophenylamino)(pyridin-2-yl)methyl)quino...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265487(2-(benzofuran-2-yl)-4-oxo-4H-benzo[d][1,3]oxazin-6...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265522(CHEMBL496155 | benzofuran-2-yl(indolin-1-yl)methan...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265522(CHEMBL496155 | benzofuran-2-yl(indolin-1-yl)methan...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265606(2-(4-chlorophenyl)-6-fluorobenzo[d]isothiazol-3(2H...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265608(4-iodo-6-phenylpyrimidine | CHEMBL497802)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50186434((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265564(2-(4-hydroxystyryl)quinolin-8-ol | 2-[2-(4-Hydroxy...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265607(3-(1H-pyrazol-3-yl)benzoic acid | CHEMBL497801)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265566(2-((4-(biphenyl-4-yl)thiazol-2-yl)methyl)thiazol-4...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265567(4-(3,4-dichlorobenzyl)-6-(thiophen-2-yl)pyridazin-...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265486(2-chloro-5-(4H-1,2,4-triazol-4-yl)benzoic acid | C...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265566(2-((4-(biphenyl-4-yl)thiazol-2-yl)methyl)thiazol-4...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265567(4-(3,4-dichlorobenzyl)-6-(thiophen-2-yl)pyridazin-...)
Affinity DataIC50:  4.30E+5nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265488(7-((3-fluorophenylamino)(pyridin-2-yl)methyl)quino...)
Affinity DataIC50:  5.30E+5nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265485(2-hydroxy-5-(1H-tetrazol-1-yl)benzoic acid | CHEMB...)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265487(2-(benzofuran-2-yl)-4-oxo-4H-benzo[d][1,3]oxazin-6...)
Affinity DataIC50:  7.30E+5nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265565(CHEMBL508697 | dibenzo[b,d]furan-3-ol)
Affinity DataIC50:  9.00E+5nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265521(2-(3-benzoylbenzofuran-5-yloxy)acetic acid | CHEMB...)
Affinity DataIC50:  9.80E+5nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50265521(2-(3-benzoylbenzofuran-5-yloxy)acetic acid | CHEMB...)
Affinity DataIC50:  1.50E+6nMAssay Description:Inhibition of human MIF-CD74 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed