Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50028017
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  2.66nMAssay Description:Activity at CCK2R-MOPR coexpressed in CHO cells co-transfected with delta-6-Galphaqi4-myr assessed as intracellular calcium release by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(N-{m-[R(+)-1]Ureaphenoxy}ethyldiglycolamidehydrazi...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(N-{m-[R(+)-1]Ureaphenoxy}ethyldiglycolamidehydrazi...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006878(1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e]...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-oxymorphyldiglyc...)
Affinity DataKi:  14.2nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  16.3nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006878(1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e]...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265494((R)-Z-N-Methyl-2-(13-(3-(3-(1-methyl-2-oxo-5-pheny...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-oxymorphyldiglyc...)
Affinity DataKi:  24.1nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  29.4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265533(2-({[(1S,5R,13R,14S,17S)-9,17-dihydroxy-4-methyl-1...)
Affinity DataKi:  29.8nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265533(2-({[(1S,5R,13R,14S,17S)-9,17-dihydroxy-4-methyl-1...)
Affinity DataKi:  40.7nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265494((R)-Z-N-Methyl-2-(13-(3-(3-(1-methyl-2-oxo-5-pheny...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(N-{m-[R(+)-1]Ureaphenoxy}ethyldiglycolamidehydrazi...)
Affinity DataKi:  57nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  71nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  77nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataEC50:  119nMAssay Description:Activity at CCK2R-MOPR coexpressed in CHO cells co-transfected with delta-6-Galphaqi4-myr assessed as intracellular calcium release by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-oxymorphyldiglyc...)
Affinity DataKi:  210nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR coexpressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-oxymorphyldiglyc...)
Affinity DataKi:  223nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  260nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(N-{m-[R(+)-1]Ureaphenoxy}ethyldiglycolamidehydrazi...)
Affinity DataKi:  356nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265533(2-({[(1S,5R,13R,14S,17S)-9,17-dihydroxy-4-methyl-1...)
Affinity DataEC50:  572nMAssay Description:Activity at CCK2R-MOPR coexpressed in CHO cells co-transfected with delta-6-Galphaqi4-myr assessed as intracellular calcium release by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed