Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 3237
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29752(macrocyclic peptidomimetic, 3f)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29751(macrocyclic peptidomimetic, 3e)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29749(macrocyclic peptidomimetic, 3c)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29748(NVP-ARV99 | macrocyclic peptidomimetic, 3b)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29753(macrocyclic peptidomimetic, 3g)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29747(macrocyclic peptidomimetic, 3a)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29751(macrocyclic peptidomimetic, 3e)
Affinity DatapH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29746(N-methyl-alanine tripeptide inhibitor, 2b)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29745(hydroxyethylene tripeptide inhibitor, 2a)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29754(macrocyclic peptidomimetic, 3h)
Affinity DataIC50: 150nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29750(macrocyclic peptidomimetic, 3d)
Affinity DataIC50: 250nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29744(hydroxyethylene tripeptide inhibitor, 1)
Affinity DataIC50: 370nMpH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29748(NVP-ARV99 | macrocyclic peptidomimetic, 3b)
Affinity DataIC50: 590nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29744(hydroxyethylene tripeptide inhibitor, 1)
Affinity DataIC50: 1.40E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29747(macrocyclic peptidomimetic, 3a)
Affinity DataIC50: 1.60E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29750(macrocyclic peptidomimetic, 3d)
Affinity DataIC50: 1.70E+3nMpH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29752(macrocyclic peptidomimetic, 3f)
Affinity DataIC50: 2.10E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29746(N-methyl-alanine tripeptide inhibitor, 2b)
Affinity DataIC50: 2.40E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29753(macrocyclic peptidomimetic, 3g)
Affinity DataIC50: 2.50E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29745(hydroxyethylene tripeptide inhibitor, 2a)
Affinity DataIC50: 3.70E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [1-453](Human)
Novartis

LigandPNGBDBM29749(macrocyclic peptidomimetic, 3c)
Affinity DataIC50: 7.60E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis

LigandPNGBDBM29754(macrocyclic peptidomimetic, 3h)
Affinity DataIC50: 8.10E+3nMpH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2009
Entry Details Article
PubMed