Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50041750
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200636BDBM50200636(4-[4-(4-Piperidin-1-ylmethyl-phenyl)-but-3-ynyl]-p...)
Affinity DataKi:  0.513nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414797BDBM50414797(CHEMBL582977)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414804BDBM50414804(CHEMBL574712)
Affinity DataKi:  0.617nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414811BDBM50414811(CHEMBL574721)
Affinity DataKi:  0.676nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414798BDBM50414798(CHEMBL575172)
Affinity DataKi:  0.724nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414800BDBM50414800(CHEMBL583182)
Affinity DataKi:  0.759nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414792BDBM50414792(CHEMBL573817)
Affinity DataKi:  0.776nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414813BDBM50414813(CHEMBL573328)
Affinity DataKi:  0.871nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414799BDBM50414799(CHEMBL573815)
Affinity DataKi:  0.891nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414806BDBM50414806(CHEMBL572845)
Affinity DataKi:  0.912nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414803BDBM50414803(CHEMBL573321)
Affinity DataKi:  0.977nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414805BDBM50414805(CHEMBL574711)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217569BDBM50217569(4-[3-(4-Piperidin-1-yl-but-1-ynyl)-benzyl]-morphol...)
Affinity DataKi:  1.17nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414812BDBM50414812(CHEMBL574720)
Affinity DataKi:  1.35nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414793BDBM50414793(CHEMBL573090)
Affinity DataKi:  1.74nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414802BDBM50414802(CHEMBL584182)
Affinity DataKi:  1.91nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414801BDBM50414801(CHEMBL574719)
Affinity DataKi:  3.47nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414810BDBM50414810(CHEMBL573564)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414809BDBM50414809(CHEMBL572388)
Affinity DataKi:  5.01nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414808BDBM50414808(CHEMBL576585)
Affinity DataKi:  5.25nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217569BDBM50217569(4-[3-(4-Piperidin-1-yl-but-1-ynyl)-benzyl]-morphol...)
Affinity DataKi:  7.08nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414807BDBM50414807(CHEMBL572612)
Affinity DataKi:  14.4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22914BDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  31.6nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414794BDBM50414794(CHEMBL574932)
Affinity DataKi:  56.2nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414796BDBM50414796(CHEMBL573808)
Affinity DataKi:  81.3nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414795BDBM50414795(CHEMBL572630)
Affinity DataKi:  83.2nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217569BDBM50217569(4-[3-(4-Piperidin-1-yl-but-1-ynyl)-benzyl]-morphol...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H1 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217569BDBM50217569(4-[3-(4-Piperidin-1-yl-but-1-ynyl)-benzyl]-morphol...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H4 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed