Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50030296
TargetRas-related C3 botulinum toxin substrate 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293841(3-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(4-methyl...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293840(N-(4-methoxy-3-(piperidin-1-ylsulfonyl)phenyl)-1H-...)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293842(1-(4-morpholinophenylamino)-1-oxopropan-2-yl 1-hyd...)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293843(CHEMBL550826 | cid_2999946 | 1,8-diamino-6-methoxy...)
Affinity DataIC50: 4.61E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293839(2-(4-fluoro-3-nitrophenylamino)-N-(4-morpholinophe...)
Affinity DataIC50: 5.72E+4nMAssay Description:Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed