Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50030748
TargetProstaglandin G/H synthase 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 40nMAssay Description:Inhibition of COX1-mediated PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 600nMAssay Description:Inhibition of COX2-mediated PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50300853([2-Methyl-1-(1-benzyl-piperidin-4-yl)-1H-indol-3-y...)
Affinity DataIC50: 1.27E+3nMAssay Description:Agonist activity at delta opioid receptor in ICR mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50300853([2-Methyl-1-(1-benzyl-piperidin-4-yl)-1H-indol-3-y...)
Affinity DataIC50: 5.16E+3nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum/longitudinal muscle with myenteric plexus assessed as inhibition of electrically-s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed