Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50004228
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  1nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  2nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  4nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480378(CHEMBL563608)
Affinity DataIC50:  7nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  8nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(CHEMBL553939 | SNX-5422)
Affinity DataIC50:  11nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(CHEMBL553939 | SNX-5422)
Affinity DataIC50:  13nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480378(CHEMBL563608)
Affinity DataIC50:  14nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480378(CHEMBL563608)
Affinity DataIC50:  16nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  32nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  41nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480374(CHEMBL560955)
Affinity DataIC50:  46nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(CHEMBL553939 | SNX-5422)
Affinity DataIC50:  61nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480372(CHEMBL562990)
Affinity DataIC50:  490nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480395(CHEMBL559840)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480380(CHEMBL552300)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480373(CHEMBL563335)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(CHEMBL553939 | SNX-5422)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480371(CHEMBL554288)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480378(CHEMBL563608)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480393(CHEMBL563500)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480370(CHEMBL562929)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480369(CHEMBL557479)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480368(CHEMBL559642)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480392(CHEMBL556391)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480398(CHEMBL560156)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480394(CHEMBL561019)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480375(CHEMBL564211)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480402(CHEMBL561497)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480376(CHEMBL558876)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480381(CHEMBL538683)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480390(CHEMBL549744)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480400(CHEMBL557478)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480382(CHEMBL565035)
Affinity DataIC50:  1.11E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480391(CHEMBL562038)
Affinity DataIC50:  1.15E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480386(CHEMBL562037)
Affinity DataIC50:  1.47E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480388(CHEMBL564702)
Affinity DataIC50:  1.81E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480383(CHEMBL561637)
Affinity DataIC50:  1.84E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480377(CHEMBL551293)
Affinity DataIC50:  2.03E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480396(CHEMBL551699)
Affinity DataIC50:  2.26E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480399(CHEMBL564559)
Affinity DataIC50:  2.29E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480401(CHEMBL561224)
Affinity DataIC50:  2.48E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480387(CHEMBL549543)
Affinity DataIC50:  2.64E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480384(CHEMBL550139)
Affinity DataIC50:  4.18E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480385(CHEMBL561498)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480389(CHEMBL556878)
Affinity DataIC50: >4.00E+6nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Serenex

Curated by ChEMBL
LigandPNGBDBM50480397(CHEMBL552094)
Affinity DataIC50: >7.00E+6nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed