Compile Data Set for Download or QSAR
Report error Found 93 Enz. Inhib. hit(s) with all data for entry = 50030391
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295489BDBM50295489((S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]thiophe...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295488BDBM50295488((R)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]thiophe...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28485BDBM28485((2S)-2-({4-[4-(1-benzofuran-2-amido)phenyl]benzene...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295479BDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295488BDBM50295488((R)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]thiophe...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28469BDBM28469((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28485BDBM28485((2S)-2-({4-[4-(1-benzofuran-2-amido)phenyl]benzene...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28470BDBM28470((2S)-2-({12-[(ethoxycarbonyl)amino]-8-oxatricyclo[...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295499BDBM50295499((S)-2-(7-((But-3-ynyloxy)carbonylamino)dibenzo[b,d...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295495BDBM50295495((S)-2-(7-(Ethoxycarbonylamino)dibenzo[b,d]thiophen...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295498BDBM50295498((S)-3-Methyl-2-(7-((2-(methylsulfonyl)ethoxy)carbo...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295491BDBM50295491((S)-2-(7-(Methoxycarbonylamino)dibenzo[b,d]thiophe...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295510BDBM50295510((S)-3-Methyl-2-(7-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295492BDBM50295492((R)-2-(7-(Methoxycarbonylamino)dibenzo[b,d]furan-3...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28485BDBM28485((2S)-2-({4-[4-(1-benzofuran-2-amido)phenyl]benzene...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28482BDBM28482((2S)-2-({11-[(methoxycarbonyl)amino]-8-oxatricyclo...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295512BDBM50295512((S)-2-(7-Aminodibenzo[b,d]furan-3-sulfonamido)-3-m...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295506BDBM50295506((S)-3-Methyl-2-(7-(3-(2-(thiophen-2-yl)ethyl)ureid...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295497BDBM50295497((S)-2-(7-(Isobutoxycarbonylamino)dibenzo[b,d]thiop...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295499BDBM50295499((S)-2-(7-((But-3-ynyloxy)carbonylamino)dibenzo[b,d...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295496BDBM50295496((S)-2-(7-(Isopropoxycarbonylamino)dibenzo[b,d]thio...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295500BDBM50295500((S)-3-Methyl-2-(7-(phenoxycarbonylamino)dibenzo[b,...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Mouse)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295479BDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 27nMAssay Description:Inhibition of mouse MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295502BDBM50295502((S)-2-(7-((4-Fluorophenoxy)carbonylamino)dibenzo[b...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295490BDBM50295490((R)-2-(7-(Methoxycarbonylamino)dibenzo[b,d]thiophe...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295509BDBM50295509((S)-2-(7-(3-Benzylureido)dibenzo[b,d]thiophene-3-s...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295501BDBM50295501((S)-3-Methyl-2-(7-(p-tolyloxycarbonylamino)dibenzo...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295479BDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28486BDBM28486((2R)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295498BDBM50295498((S)-3-Methyl-2-(7-((2-(methylsulfonyl)ethoxy)carbo...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295493BDBM50295493((S)-2-(7-Aminodibenzo[b,d]thiophene-3-sulfonamido)...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295511BDBM50295511((S)-3-Methyl-2-(7-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295485BDBM50295485((S)-3-Methyl-2-(8-(methylsulfonamido)dibenzo[b,d]t...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295495BDBM50295495((S)-2-(7-(Ethoxycarbonylamino)dibenzo[b,d]thiophen...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28469BDBM28469((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295484BDBM50295484((R)-3-Methyl-2-(8-(methylsulfonamido)dibenzo[b,d]t...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295489BDBM50295489((S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]thiophe...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295479BDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295479BDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 72nMAssay Description:Inhibition of rat MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295480BDBM50295480((R)-2-(Dibenzo[b,d]thiophene-2-sulfonamido)-3-meth...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295508BDBM50295508((S)-3-Methyl-2-(7-(3-phenylureido)dibenzo[b,d]thio...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28470BDBM28470((2S)-2-({12-[(ethoxycarbonyl)amino]-8-oxatricyclo[...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295494BDBM50295494((R)-2-(7-(Ethoxycarbonylamino)dibenzo[b,d]thiophen...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295479BDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28469BDBM28469((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295511BDBM50295511((S)-3-Methyl-2-(7-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295496BDBM50295496((S)-2-(7-(Isopropoxycarbonylamino)dibenzo[b,d]thio...)
Affinity DataIC50: 147nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295505BDBM50295505((S)-3-Methyl-2-(7-(3-(2-(thiophen-2-yl)ethyl)ureid...)
Affinity DataIC50: 187nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295506BDBM50295506((S)-3-Methyl-2-(7-(3-(2-(thiophen-2-yl)ethyl)ureid...)
Affinity DataIC50: 187nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295509BDBM50295509((S)-2-(7-(3-Benzylureido)dibenzo[b,d]thiophene-3-s...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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