Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50038934
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299471BDBM50299471(Ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxy...)
Affinity DataIC50: 750nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299477BDBM50299477(Propyl 2-amino-4-methyl-5-phenylthiophene-3-carbox...)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299481BDBM50299481(2-isothiocyanato-4-methyl-5-phenylthiophene-3-carb...)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299478BDBM50299478(Tert-Butyl 2-amino-4-methyl-5-phenylthiophene-3-ca...)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031704BDBM50031704(2-Amino-4-methyl-pentanedioic acid | (2S,4R)-2-ami...)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299472BDBM50299472(Methyl 2-amino-4-methyl-5-phenylthiophene-3-carbox...)
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299476BDBM50299476(Ethyl 2-amino-4,5-diphenylthiophene-3-carboxylate ...)
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299475BDBM50299475(Ethyl 2-amino-5-(2-chlorophenyl)-4-methylthiophene...)
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31772BDBM31772(Brentan | 1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dich...)
Affinity DataIC50: 6.50E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299473BDBM50299473(Ethyl 2-amino-5-(4-methoxyphenyl)-4-methylthiophen...)
Affinity DataIC50: 8.60E+3nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299485BDBM50299485(Ethyl 2-chloro-4-methyl-5-phenylthiophene-3-carbox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299480BDBM50299480((2-Amino-4-methyl-5-phenylthiophen-3-yl)(phenyl)me...)
Affinity DataIC50: 1.06E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299474BDBM50299474(Ethyl 2-amino-5-(4-fluorophenyl)-4-methylthiophene...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299484BDBM50299484(Ethyl 2-(cyanodiazenyl)-4-methyl-5-phenylthiophene...)
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185321BDBM50185321(7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carboni...)
Affinity DataIC50: 2.30E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299472BDBM50299472(Methyl 2-amino-4-methyl-5-phenylthiophene-3-carbox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant GluR5 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002369BDBM50002369(Digensaeure | (3S,4R)-3-(carboxymethyl)-4-(prop-1-...)
Affinity DataEC50:  3.36E+4nMAssay Description:Agonist activity at recombinant GluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299482BDBM50299482(Ethyl 2-(3,3-dimethyltriaz-1-enyl)-4-methyl-5-phen...)
Affinity DataIC50: 3.80E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299483BDBM50299483(Ethyl 4-methyl-2-(morpholinodiazenyl)-5-phenylthio...)
Affinity DataIC50: 5.40E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299479BDBM50299479(2-Amino-4-methyl-5-phenylthiophene-3-carbonitrile ...)
Affinity DataIC50: 7.10E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50207594BDBM50207594(2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxali...)
Affinity DataIC50: 7.40E+4nMAssay Description:Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26431BDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  2.70E+5nMAssay Description:Agonist activity at recombinant GluR6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002369BDBM50002369(Digensaeure | (3S,4R)-3-(carboxymethyl)-4-(prop-1-...)
Affinity DataEC50:  2.99E+5nMAssay Description:Agonist activity at recombinant GluR6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit£T Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26431BDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  6.31E+5nMAssay Description:Agonist activity at recombinant GluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed