Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50030878
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303246BDBM50303246((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303254BDBM50303254((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(2-fluoro-3-methyl...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303239BDBM50303239((1S,3'R,4'S,5'S,6'R)-5-chloro-4-(1-(4-ethylphenyl)...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303242BDBM50303242((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303256BDBM50303256((1S,3'R,4'S,5'S,6'S)-5-chloro-4-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303257BDBM50303257((1S,3'R,4'S,5'S,6'R)-5-chloro-4-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303240BDBM50303240(O-spiroketal glucoside | (1S,3'R,4'S,5'S,6'R)-5-ch...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303243BDBM50303243((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20880BDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303238BDBM50303238((1S,3'R,4'S,5'S,6'R)-5-chloro-4-((4-ethylphenyl)di...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303244BDBM50303244((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303247BDBM50303247((1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-5-fluoro-6'...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303235BDBM50303235((1S,3'R,4'S,5'S,6'R)-6'-(azidomethyl)-5-chloro-4-(...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303255BDBM50303255((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303245BDBM50303245((1S,3'R,4'S,5'S,6'R)-6-(4-tert-butylbenzyl)-5-chlo...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303237BDBM50303237(((1S,3'R,4'S,5'S,6'R)-5-chloro-3',4',5'-trihydroxy...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303259BDBM50303259(((1S,3'R,4'S,5'S,6'R)-5-chloro-4-(4-ethylbenzyl)-3...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303248BDBM50303248((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(3-chloro-4-ethoxy...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303258BDBM50303258((1S,3'R,4'S,5'S,6'R)-5-chloro-4-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303241BDBM50303241((1S,3'R,4'S,5'S,6'R)-6-(4-ethoxybenzyl)-6'-(hydrox...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303236BDBM50303236((1S,3'R,4'S,5'S,6'R)-6'-(aminomethyl)-5-chloro-4-(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303252BDBM50303252((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-fluoro-2-methyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303242BDBM50303242((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303243BDBM50303243((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303256BDBM50303256((1S,3'R,4'S,5'S,6'S)-5-chloro-4-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20880BDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 890nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303252BDBM50303252((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-fluoro-2-methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303255BDBM50303255((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303251BDBM50303251((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303250BDBM50303250((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-ethoxy-2-methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303235BDBM50303235((1S,3'R,4'S,5'S,6'R)-6'-(azidomethyl)-5-chloro-4-(...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303249BDBM50303249((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(2-chloro-4-ethoxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303260BDBM50303260((1S,3'R,4'S,5'S,6'R)-4-(4-ethylbenzyl)-6'-(hydroxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303250BDBM50303250((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-ethoxy-2-methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303253BDBM50303253((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(2-ethoxy-4-fluoro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SGLT2 transfected in HEK293.ETN cells assessed as AMG uptake after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303240BDBM50303240(O-spiroketal glucoside | (1S,3'R,4'S,5'S,6'R)-5-ch...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303254BDBM50303254((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(2-fluoro-3-methyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303238BDBM50303238((1S,3'R,4'S,5'S,6'R)-5-chloro-4-((4-ethylphenyl)di...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303244BDBM50303244((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303257BDBM50303257((1S,3'R,4'S,5'S,6'R)-5-chloro-4-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303246BDBM50303246((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303259BDBM50303259(((1S,3'R,4'S,5'S,6'R)-5-chloro-4-(4-ethylbenzyl)-3...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303247BDBM50303247((1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-5-fluoro-6'...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303239BDBM50303239((1S,3'R,4'S,5'S,6'R)-5-chloro-4-(1-(4-ethylphenyl)...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303245BDBM50303245((1S,3'R,4'S,5'S,6'R)-6-(4-tert-butylbenzyl)-5-chlo...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303253BDBM50303253((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(2-ethoxy-4-fluoro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303251BDBM50303251((1S,3'R,4'S,5'S,6'R)-5-chloro-6'-(hydroxymethyl)-6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303241BDBM50303241((1S,3'R,4'S,5'S,6'R)-6-(4-ethoxybenzyl)-6'-(hydrox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303249BDBM50303249((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(2-chloro-4-ethoxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303248BDBM50303248((1S,3'R,4'S,5'S,6'R)-5-chloro-6-(3-chloro-4-ethoxy...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human SGLT1 transfected in COS-7 cells assessed as AMG uptake after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 53 total ) | Next | Last >>
Jump to: