Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 3477
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35298BDBM35298(benzoylguanidine, 18)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35303BDBM35303(isonicotinoyl guanidine, 23)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35299BDBM35299(benzoylguanidine, 19)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35300BDBM35300(benzoylguanidine, 20)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35313BDBM35313(nicotinoyl guanidine, 33)
Affinity DataIC50: 3.30nMT: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35305BDBM35305(heteroaroylguanidine, 25)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35311BDBM35311(nicotinoyl guanidine, 31)
Affinity DataIC50: 4nMT: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35302BDBM35302(nicotinoyl guanidine, 22)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35294BDBM35294(benzoylguanidine, 14)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35312BDBM35312(nicotinoyl guanidine, 32)
Affinity DataIC50: 5nMT: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35306BDBM35306(heteroaroylguanidine, 26)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35292BDBM35292(benzoylguanidine, 12)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35297BDBM35297(benzoylguanidine, 17)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35315BDBM35315(nicotinoyl guanidine, 35)
Affinity DataIC50: 6nMT: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35293BDBM35293(benzoylguanidine, 13)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35307BDBM35307(heteroaroylguanidine, 27)
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35316BDBM35316(BMS-344577)
Affinity DataIC50: 9nMT: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35309BDBM35309(nicotinoyl guanidine, 29)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35296BDBM35296(benzoylguanidine, 16)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35285BDBM35285(sulfonylguanidine, 5)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35314BDBM35314(nicotinoyl guanidine, 34)
Affinity DataIC50: 12nMT: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35283BDBM35283(CHEMBL551991 | cyanoguanidine, 3)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35286BDBM35286(sulfamoylguanidine, 6)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35291BDBM35291(carbamoylguanidine, 11)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35288BDBM35288(acetylguanidine, 8)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35310BDBM35310(nicotinoyl guanidine, 30)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35295BDBM35295(benzoylguanidine, 15)
Affinity DataIC50: 18nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35287BDBM35287(sulfonylguanidine, 7)
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35284BDBM35284(nitroguanidine, 4)
Affinity DataIC50: 25nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35290BDBM35290(carbamoylguanidine, 10)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 26351BDBM26351(CHEMBL196803 | 2-{[(2-methyl-1-benzofuran-5-yl)ami...)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35289BDBM35289(ethoxylcarbonylguanidine, 9)
Affinity DataIC50: 32nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35304BDBM35304(heteroaroylguanidine, 24)
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35301BDBM35301(picolinoyl guanidine, 21)
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 35308BDBM35308(tetrazoloyl guanidine, 28)
Affinity DataIC50: 56nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 26350BDBM26350(3-(3-methylphenyl)-1-[(3S)-2-oxo-1-[2-oxo-2-(pyrro...)
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2009
Entry Details Article
PubMed